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加强负责任的抗菌药物使用并减轻抗菌药物耐药性负担的生物安全措施。

Biosecurity Practices to Enhance Responsible Antimicrobial Use and Reduce the Burden of Antimicrobial Resistance.

作者信息

Plummer Paul, Fajt Virginia R

机构信息

College of Veterinary Medicine, University of Tennessee, A102 Veterinary Medical Center, 2407 River Drive, Knoxville, TN 37996-4503, USA.

College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, 4466 TAMU, College Station, TX 77843-4466, USA.

出版信息

Vet Clin North Am Food Anim Pract. 2025 Mar;41(1):25-37. doi: 10.1016/j.cvfa.2024.11.002. Epub 2024 Nov 16.

Abstract

The article shows the case for using biosecurity measures to mitigate antimicrobial resistance (AMR) in beef and dairy production through actions of veterinarians and animal caretakers. The impact of biosecurity on the prevention of bacterial infections is discussed, with the goal being to reduce the need for antimicrobial drugs. This is expected to reduce the selection for AMR in pathogens and commensal bacterial organisms in beef and dairy animals. The potential impact of biosecurity on the prevention of dissemination of antimicrobial resistant bacteria and AMR genes in the environment is also described.

摘要

本文通过兽医和动物饲养员的行动,展示了利用生物安全措施减轻牛肉和奶制品生产中抗菌药物耐药性(AMR)的实例。文中讨论了生物安全对预防细菌感染的影响,目标是减少对抗菌药物的需求。这有望减少牛肉和奶牛中病原体和共生细菌对抗菌药物耐药性的选择。文中还描述了生物安全对预防抗菌药物耐药细菌和AMR基因在环境中传播的潜在影响。

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