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细胞减灭术和腹腔热灌注化疗(HIPEC)在胰腺癌治疗中的新作用

The Emerging Role of Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Pancreatic Cancer.

作者信息

Thiels Cornelius, Grotz Travis E

机构信息

Division of Hepatobiliary and Pancreas Surgery, Mayo Clinic, Rochester, Minnesota, USA.

出版信息

J Surg Oncol. 2024 Nov;130(6):1257-1262. doi: 10.1002/jso.27880. Epub 2024 Nov 17.

Abstract

Peritoneal spread is a frequent cause of metastasis in both the synchronous and metachronous settings for patients with pancreatic cancer. Recent improvements in systemic chemotherapy for pancreatic cancer may now allow for the careful selection of patients with oligometastatic disease isolated to the peritoneum who may benefit from consolidative cytoreduction and HIPEC.

摘要

腹膜播散是胰腺癌患者同时性和异时性转移的常见原因。目前,胰腺癌全身化疗的进展使得能够谨慎选择那些仅腹膜存在寡转移病灶且可能从巩固性细胞减灭术和腹腔内热灌注化疗(HIPEC)中获益的患者。

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