[褪黑素对甲状腺功能影响的季节性特征]
[Seasonal characteristics of the effect of melatonin on thyroid function].
作者信息
Rom-Bugoslavskaia E S, Shcherbakova V S
出版信息
Biull Eksp Biol Med. 1986 Mar;101(3):268-9.
PMID:3955205
Abstract
Changes in pituitary-thyroid axis sensitivity to bioactive component of pineal gland, melatonin, have been detected. In winter (short days) melatonin (100 micrograms/100 g of rat body weight) decreased T3 T4, TSH content and 131I uptake by thyroid tissue. However, it was noted that in summer (long photoperiod) the same injection caused suppression of T3 plasma level and 131I uptake ability of the thyroid gland, with T4 and TSH blood levels remaining significantly increased.
摘要
已检测到垂体-甲状腺轴对松果体生物活性成分褪黑素的敏感性变化。在冬季（短日照），褪黑素（100微克/100克大鼠体重）可降低甲状腺组织中T3、T4、促甲状腺激素（TSH）含量以及131碘摄取量。然而，值得注意的是，在夏季（长光照周期），相同剂量的注射会抑制血浆中T3水平以及甲状腺的131碘摄取能力，而血液中T4和TSH水平仍显著升高。
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