[脑啡肽对休克时钙调节内分泌腺功能的影响]
[Effect of enkephalins on the function of the calcium-regulating endocrine glands in shock].
作者信息
Zoloev G K, Slepushkin V D
出版信息
Biull Eksp Biol Med. 1986 Mar;101(3):284-7.
The experiments on white rats weighing 180-220 g have shown that in traumatic and hemorrhagic shock the initial increase in parathyroid hormone blood concentration is followed by the decrease of functional activity of parathyroid glands. Calcitonin concentration is found to increase during the first hours of shock. The changes in calcium-regulating gland function result in significant disturbances of calcium exchange during shock. The injection of synthetic leu-enkephalin analogs to rats with shock leads to normalization of calcium-regulating endocrine glands function.
对体重180 - 220克的白鼠进行的实验表明，在创伤性和失血性休克中，甲状旁腺激素血浓度最初升高，随后甲状旁腺的功能活性降低。发现降钙素浓度在休克的最初几个小时内升高。钙调节腺功能的变化导致休克期间钙交换的显著紊乱。给休克大鼠注射合成亮脑啡肽类似物可使钙调节内分泌腺功能恢复正常。
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