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Successful treatment of discoid lupus erythematosus with tapinarof 1% cream monotherapy.

作者信息

Garg Kareena S, Tjahjono Leonardo

机构信息

Department of Dermatology, Georgetown University School of Medicine, Washington, District of Columbia.

Department of Dermatology, George Washington School of Medicine, Washington, District of Columbia.

出版信息

JAAD Case Rep. 2024 Sep 30;54:1-2. doi: 10.1016/j.jdcr.2024.09.010. eCollection 2024 Dec.

DOI:10.1016/j.jdcr.2024.09.010
PMID:39552756
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11566309/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c27/11566309/e0bfa61df48e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c27/11566309/6fd4f6113d4f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c27/11566309/e0bfa61df48e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c27/11566309/6fd4f6113d4f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c27/11566309/e0bfa61df48e/gr2.jpg

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本文引用的文献

1
AhR agonist tapinarof ameliorates lupus autoimmunity by suppressing Tfh cell differentiation via regulation of the JAK2-STAT3 signaling pathway.芳香烃受体激动剂他克莫司通过调节 JAK2-STAT3 信号通路抑制滤泡辅助性 T 细胞分化改善狼疮自身免疫。
Immun Inflamm Dis. 2023 Jun;11(6):e903. doi: 10.1002/iid3.903.
2
The key player in the pathogenesis of environmental influence of systemic lupus erythematosus: Aryl hydrocarbon receptor.系统性红斑狼疮环境影响发病机制中的关键因素：芳香烃受体。
Front Immunol. 2022 Aug 30;13:965941. doi: 10.3389/fimmu.2022.965941. eCollection 2022.
3
Phase 3 Trials of Tapinarof Cream for Plaque Psoriasis.
他卡西醇乳膏治疗斑块状银屑病的 3 期临床试验。
N Engl J Med. 2021 Dec 9;385(24):2219-2229. doi: 10.1056/NEJMoa2103629.
4
Tapinarof in the treatment of psoriasis: A review of the unique mechanism of action of a novel therapeutic aryl hydrocarbon receptor-modulating agent.他卡西醇治疗银屑病：新型芳香烃受体调节剂独特作用机制的综述。
J Am Acad Dermatol. 2021 Apr;84(4):1059-1067. doi: 10.1016/j.jaad.2020.10.085. Epub 2020 Nov 3.
5
Aryl Hydrocarbon Receptor in Atopic Dermatitis and Psoriasis.芳香烃受体在特应性皮炎和银屑病中的作用。
Int J Mol Sci. 2019 Oct 31;20(21):5424. doi: 10.3390/ijms20215424.