Koga Yuichi, Sato Manabu, Sadashima Eiji, Ushigusa Jun, Kawasaki Hiromitsu, Kamohara Keiji
Department of Cardiovascular Surgery, Saga-Ken Medical Centre Koseikan, Saga, Japan.
Medical Research Institute, Saga-Ken Medical Centre Koseikan, Saga, Japan.
SAGE Open Med. 2024 Nov 16;12:20503121241296566. doi: 10.1177/20503121241296566. eCollection 2024.
Postoperative atrial fibrillation occurs in 27% to 40% of patients after cardiac surgery. One cause of postoperative atrial fibrillation is pericardial effusion, which can be a significant source of inflammation. In this study, we investigated the effect of a drain placed in a posterior site to the heart to reduce pericardial effusion in the early postoperative period to prevent postoperative atrial fibrillation.
Participants were patients who underwent initial standby aortic valve replacement at Saga-Ken Medical Centre Koseikan from January 2010 to December 2021. Patients with a history of atrial fibrillation, complex surgery, or emergency surgery were excluded. The patients were divided into two groups: those with a posterior cardiac drain in addition to the usual intrapericardial and subpleural drains from September 2017 (group P) and those without posterior cardiac drain from January 2010 to August 2017 (group N). Multiple logistic regression analysis was performed to evaluate the usefulness of posterior cardiac drain.
Of the 79 patients included the study, 40 were male and groups P and N comprised 27 and 52 patients, respectively. Of the 79 patients, 32 developed postoperative atrial fibrillation; among whom, 7/27 (25.9%) had posterior cardiac drain and 25/52 (48.1%) had no posterior cardiac drain ( = 0.09). When adjusted for body surface area, left ventricular end-diastolic and left atrial diameter, the incidence of postoperative atrial fibrillation was significantly lower in group P than in group N (adjusted odds ratio 0.270, 95% confidence interval 0.077-0.953, = 0.042). Furthermore, no patient in the group P underwent postoperative thoracentesis in the subanalysis.
The results suggest that early postoperative reduction of pericardial effusion by posterior cardiac drain placement may reduce the incidence of postoperative atrial fibrillation.
心脏手术后,27%至40%的患者会发生术后房颤。术后房颤的一个原因是心包积液,它可能是炎症的重要来源。在本研究中,我们调查了在心脏后方放置引流管以减少术后早期心包积液,从而预防术后房颤的效果。
研究对象为2010年1月至2021年12月在佐贺县立医疗中心小关医院接受初次择期主动脉瓣置换术的患者。排除有房颤病史、复杂手术或急诊手术的患者。患者分为两组:2017年9月起除常规的心包内和胸膜下引流管外还放置心脏后方引流管的患者(P组),以及2010年1月至2017年8月未放置心脏后方引流管的患者(N组)。进行多因素逻辑回归分析以评估心脏后方引流管的有效性。
纳入研究的79例患者中,男性40例,P组和N组分别有27例和52例患者。79例患者中,32例发生术后房颤;其中,7/27(25.9%)有心脏后方引流管,25/52(48.1%)没有心脏后方引流管(P = 0.09)。校正体表面积、左心室舒张末期内径和左心房直径后,P组术后房颤的发生率显著低于N组(校正比值比0.270,95%置信区间0.077 - 0.953,P = 0.042)。此外,在亚分析中,P组没有患者接受术后胸腔穿刺。
结果表明,通过放置心脏后方引流管在术后早期减少心包积液可能会降低术后房颤的发生率。