Lim Mi Hee, Lee Chee-Hoon, Ju Min Ho, Je Hyung Gon
Department of Cardiovascular and Thoracic Surgery, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Pusan National University College of Medicine, Yangsan-si, Gyeongsangnam-do, Republic of Korea.
J Thorac Dis. 2024 Oct 31;16(10):6664-6676. doi: 10.21037/jtd-24-928. Epub 2024 Oct 14.
Minimally invasive procedures are increasingly implemented in aortic valve replacement (AVR) surgeries to minimize surgical trauma and achieve early patient recovery. We aimed to compare between short- and mid-term outcomes for isolated AVR using the representative minimally invasive approaches of right anterior mini-thoracotomy (RAMT) and partial upper sternotomy [J-sternotomy (JS)].
Patients (n=832) who had undergone surgical AVR between March 2009 and September 2022 were included. We retrospectively examined and compared data from these two minimally invasive approaches, and performed propensity score matching to account for differences in patient baseline characteristics. Early outcomes and late mortality were compared between the matched groups.
After applying exclusion criteria, the study comprised 315 patients who underwent RAMT and 92 who underwent JS. Patients who underwent JS had more comorbidities, compared with those who underwent RAMT. Propensity score matching of 16 variables yielded similar groups for comparison (n=90). Thirty-day mortality was similar between the two groups (0% 1%, respectively; P>0.99). In the RAMT group, the rate of on-table extubation was significantly higher (P<0.001), whereas the blood transfusion rate was lower and length of stay was shorter, compared with the JS group. The 5-year survival rate was higher in the RAMT group than in the JS group (95.0% 85.6%, respectively; P=0.03).
AVR via RAMT was associated with improved early clinical outcomes, shorter length of stay, and increased survival, compared with JS. Despite the technical challenges associated with RAMT, this procedure can be considered a primary strategy for isolated AVR.
在主动脉瓣置换术(AVR)手术中,越来越多地采用微创手术以将手术创伤降至最低并实现患者早期康复。我们旨在比较采用右前小切口开胸术(RAMT)和部分上胸骨切开术[J形胸骨切开术(JS)]这两种具有代表性的微创手术方法进行单纯AVR的短期和中期结果。
纳入2009年3月至2022年9月期间接受外科AVR手术的患者(n = 832)。我们回顾性检查并比较了这两种微创手术方法的数据,并进行倾向评分匹配以考虑患者基线特征的差异。对匹配组之间的早期结果和晚期死亡率进行了比较。
应用排除标准后,该研究包括315例行RAMT手术的患者和92例行JS手术的患者。与接受RAMT手术的患者相比,接受JS手术的患者合并症更多。对16个变量进行倾向评分匹配后得到了可进行比较的相似组(n = 90)。两组的30天死亡率相似(分别为0%和1%;P>0.99)。与JS组相比,RAMT组的术中拔管率显著更高(P<0.001),而输血率更低且住院时间更短。RAMT组的5年生存率高于JS组(分别为95.0%和85.6%;P = 0.03)。
与JS相比,通过RAMT进行AVR与更好的早期临床结果、更短的住院时间和更高的生存率相关。尽管RAMT存在技术挑战,但该手术可被视为单纯AVR的主要策略。