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鞘内给药用于成人疼痛和痉挛的管理:英国疼痛学会最佳临床实践建议

Intrathecal drug delivery for the management of pain and spasticity in adults: British Pain Society's recommendations for best clinical practice.

作者信息

Eldabe Sam, Duarte Rui, Thomson Simon, Bojanic Stana, Farquhar-Smith Paul, Bagchi Somnath, Farquhar Lis, Wetherill Bill, Copley Sue

机构信息

Department of Pain Medicine, The James Cook University Hospital, Middlesbrough, UK.

Liverpool Reviews and Implementation Group, Department of Health Data Science, University of Liverpool, Liverpool, UK.

出版信息

Br J Pain. 2024 Sep 7:20494637241280356. doi: 10.1177/20494637241280356.

Abstract

The British Pain Society updated their recommendations on intrathecal drug delivery (ITDD) for the management of pain and spasticity in adults. The recommendations are primarily evidence based but where necessary comprise the consensus opinion of the working group. The recommendations are accompanied by information for patients and their carers, intended to inform and support patients in their decision making. The updated guidance includes recent evidence base of ITDD use in pain and spasticity, address the issues of drug pump compatibility following the latest manufacturer and Medicines and Healthcare products Regulatory Agency (MHRA) recommendations as well as provide an update on the indications and complication management particularly endocrine complications and intrathecal granuloma formation.

摘要

英国疼痛协会更新了关于鞘内药物递送(ITDD)用于成人疼痛和痉挛管理的建议。这些建议主要基于证据,但在必要时包含了工作组的共识意见。建议还附带了针对患者及其护理人员的信息,旨在为患者的决策提供信息和支持。更新后的指南包括ITDD用于疼痛和痉挛的最新证据基础,根据最新的制造商和药品及医疗产品监管局(MHRA)建议解决药物泵兼容性问题,并提供关于适应症和并发症管理的最新信息,特别是内分泌并发症和鞘内肉芽肿形成。

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