Hallal Marwa, Tannous Zeina
Department of Dermatology, Faculty of Medicine, Lebanese American University, Byblos, LBN.
Department of Dermatology, Lebanese American University Medical Center - Rizk Hospital, Beirut, LBN.
Cureus. 2024 Oct 16;16(10):e71614. doi: 10.7759/cureus.71614. eCollection 2024 Oct.
Varicella-zoster virus (VZV) can lead to rare complications such as cutaneous vasculitis. We present a unique case of post-zoster cutaneous vasculitis in an 82-year-old male, occurring alongside acute calcium pyrophosphate deposition disease (CPPD), a previously undocumented association. The patient initially presented with a painful zoster rash and hand swelling, treated with oral acyclovir. Persistent swelling led to a diagnosis of CPPD in the wrist, managed with prednisone and colchicine. A biopsy of purplish discoloration at the zoster site confirmed vasculitis, which resolved after treatment. This case underscores the importance of recognizing post-zoster vasculitis, even in immunocompetent individuals, and suggests a potential link with CPPD that warrants further investigation.
水痘带状疱疹病毒（VZV）可导致罕见的并发症，如皮肤血管炎。我们报告了一例82岁男性的带状疱疹后皮肤血管炎的独特病例，该病例同时伴有急性焦磷酸钙沉积病（CPPD），这是一种以前未被记录的关联。患者最初表现为疼痛性带状疱疹皮疹和手部肿胀，接受口服阿昔洛韦治疗。持续肿胀导致手腕部被诊断为CPPD，采用泼尼松和秋水仙碱治疗。对带状疱疹部位的紫色变色区域进行活检证实为血管炎，治疗后病情得到缓解。该病例强调了即使在免疫功能正常的个体中识别带状疱疹后血管炎的重要性，并提示了与CPPD之间的潜在联系，值得进一步研究。
