Okano Hiroshi, Asakawa Hiroki, Mukai Katsumi, Nishimura Akira, Hamada Takashi, Asakawa Kana, Baba Youichirou, Murata Tetsuya
Gastroenterology, Suzuka General Hospital, Suzuka, JPN.
Gastroenterology, Suzuka general hospital, Suzuka, JPN.
Cureus. 2024 Oct 16;16(10):e71656. doi: 10.7759/cureus.71656. eCollection 2024 Oct.
A 70-year-old man was incidentally diagnosed with a single hepatic mass lesion in his right hepatic lobe during a computed tomography scan. The lesion exhibited consistent enhancement with contrast agents on computed tomography (CT), magnetic resonance imaging (MRI), and hepatic arterial angiography. While a definitive diagnosis could not be made preoperatively, the lesion was surgically resected due to its slight enlargement over two months, suggesting a potential malignancy. Pathological examination revealed the lesion to be a bile duct adenoma (BDA). The BDA was characterized by dense proliferative small gland cavities containing several to dozens of cells. Immunohistochemical staining showed positive CK7 and negative p53. The patient remains alive and free of recurrence five years after hepatectomy. Although BDAs are rare benign hepatic tumors, they carry a risk of harboring or developing malignant tissue, such as cholangiocarcinoma. Therefore, BDAs or lesions suspicious of BDA should be surgically resected or closely monitored.
一名70岁男性在计算机断层扫描时偶然发现右肝叶有一个单发肝脏肿块病变。该病变在计算机断层扫描（CT）、磁共振成像（MRI）和肝动脉血管造影中表现出与造影剂一致的强化。虽然术前未能做出明确诊断，但由于该病变在两个月内略有增大，提示可能为恶性，因此进行了手术切除。病理检查显示该病变为胆管腺瘤（BDA）。BDA的特征是密集增生的小腺腔，含有几个到几十个细胞。免疫组织化学染色显示CK7阳性，p53阴性。肝切除术后五年，患者仍然存活且无复发。虽然BDA是罕见的肝脏良性肿瘤，但它们有 harboring 或发展为恶性组织（如胆管癌）的风险。因此，BDA或疑似BDA的病变应进行手术切除或密切监测。 （注：原英文中“harboring”这个词在这里结合语境推测可能是“隐匿”之类意思，但直接翻译不好处理，这里保留英文供你参考确认准确意思。）
