Mukenschnabl Kami, Ina Emily A, Bacoat-Jones Toni
Obstetrics and Gynecology, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, USA.
Osteopathic Medical School, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.
Cureus. 2024 Oct 18;16(10):e71774. doi: 10.7759/cureus.71774. eCollection 2024 Oct.
This study investigates the various methods of pain management during the insertion of intrauterine devices (IUDs) in nulliparous women. Currently, the only recommended method of pain management is 800 mg of ibuprofen taken one hour before insertion of the IUD. However, women continue to experience pain during the procedure. A scoping review was conducted using CINAHL, Medline, Web of Science, and Embase with inclusion criteria being English peer-reviewed articles from the last 10 years, involving nulliparous women of at least 18 years of age. The research reveals that management to minimize pain during IUD insertion can include oral analgesics, cervical blocks, and cervical softening and dilation with prostaglandins. The effect of pain management when using these techniques was further examined throughout the various steps of IUD placement, including cervical grasping, IUD insertion, and post IUD insertion. Ibuprofen is the current recommended analgesic; however, studies show that there was no significant reduction in pain found when ibuprofen is used. Alternatively, 500 mg of naproxen sodium taken prior to IUD insertion showed a significant reduction in post-IUD insertion pain (p=0.01) but did not show any significant reduction in pain during cervical grasping or during IUD insertion into the uterus. Cervical blocks using 1% lidocaine were shown to decrease pain during cervical gripping (p=0.002) and IUD insertion compared to the control group (p=0.005). The results of cervical blocks differed based on whether 1% lidocaine was injected or if a 2% lidocaine gel was used, but no significance was shown. Furthermore, cervical softening and dilation with dinoprostone 3 mg and misoprostol 3 mg demonstrated a reduction in pain during all stages of IUD insertion and after insertion (p<0.01). Pharmacological interventions with oral analgesics, lidocaine, and prostaglandins, such as dinoprostone and misoprostol, have all demonstrated some level of pain control during the IUD insertion procedure, but the use of prostaglandins and 2% lidocaine gel has been demonstrated to have the most clinically significant effect on pain control. Additionally, there has been some research examining the impact of verbal analgesics, which involves the provider using a calm, soothing voice and slow speech to put the patient at ease, and the role that anxiety about IUD insertion can influence pain, but further research is needed to determine its significance. This research provides valuable insight into enhancing the improvement of pain during and after the insertion of IUDs for nulliparous women.
本研究调查了未生育女性宫内节育器(IUD)置入过程中的各种疼痛管理方法。目前,唯一推荐的疼痛管理方法是在IUD置入前一小时服用800毫克布洛芬。然而,女性在手术过程中仍会感到疼痛。使用CINAHL、Medline、Web of Science和Embase进行了一项范围综述,纳入标准为过去10年的英文同行评审文章,涉及至少18岁的未生育女性。研究表明,在IUD置入过程中尽量减少疼痛的管理方法可包括口服镇痛药、宫颈阻滞以及使用前列腺素进行宫颈软化和扩张。在IUD放置的各个步骤中,包括宫颈钳夹、IUD置入和IUD置入后,进一步检查了使用这些技术时疼痛管理的效果。布洛芬是目前推荐的镇痛药;然而,研究表明,使用布洛芬时疼痛并未显著减轻。另外,在IUD置入前服用500毫克萘普生钠可使IUD置入后疼痛显著减轻(p = 0.01),但在宫颈钳夹或IUD置入子宫过程中疼痛并未显著减轻。与对照组相比,使用1%利多卡因进行宫颈阻滞可减轻宫颈钳夹时的疼痛(p = 0.002)以及IUD置入时的疼痛(p = 0.005)。宫颈阻滞的结果因注射的是1%利多卡因还是使用2%利多卡因凝胶而有所不同,但未显示出显著差异。此外,使用3毫克地诺前列酮和3毫克米索前列醇进行宫颈软化和扩张可减轻IUD置入各阶段及置入后的疼痛(p < 0.01)。口服镇痛药、利多卡因以及前列腺素(如地诺前列酮和米索前列醇)的药物干预在IUD置入过程中均显示出一定程度的疼痛控制效果,但使用前列腺素和2%利多卡因凝胶已被证明对疼痛控制具有最显著的临床效果。此外,有一些研究探讨了言语镇痛的影响,即医护人员用平静、舒缓的声音和缓慢的语速让患者放松,以及对IUD置入的焦虑对疼痛的影响,但需要进一步研究以确定其重要性。这项研究为改善未生育女性IUD置入过程中和置入后的疼痛提供了有价值的见解。