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整形与重建手术患者围手术期抗栓治疗的管理:基于现行指南的实用工具

Perioperative Management of Antithrombotic Therapy in Patients Undergoing Plastic and Reconstructive Surgery: A Practical Tool Based on Current Guidelines.

作者信息

Behroozian Tara, Fang Evan, Douketis James, Retrouvey Helene, Thoma Achilles

机构信息

Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.

Department of Medicine, McMaster University, Hamilton, ON, Canada.

出版信息

Plast Surg (Oakv). 2024 May 29:22925503241256654. doi: 10.1177/22925503241256654.

Abstract

Given the aging population, plastic surgeons are increasingly faced with the challenge of balancing procedural bleeding risk with thromboembolic risk in patients receiving antithrombotic therapies undergoing elective procedures. Guideline recommendations remain unclear in this population, which contributes to heterogeneity in clinical practices. We present a practical approach that summarizes guideline recommendations to facilitate the perioperative management of patients requiring surgery who are already on antithrombotic agents. Due to the scarcity of plastic surgery-specific guidelines, recommendations were primarily adapted from the 2022 American College of Chest Physicians guidelines on perioperative management of antithrombotic therapy as they are recognized as authoritative and widely used in clinical practice. A clinical practice conceptual framework was adapted based on preexisting guidelines, dividing decision-making into 3 steps: (1) assessing the procedural bleeding risk; (2) assessing the patients' thromboembolic risk; and (3) determining appropriate management according to antithrombotic agent type. Specific indications are provided for continuing, stopping, and bridging anticoagulants and antiplatelet agents, as well as for consultation with a cardiologist or hematologist. The present framework can be implemented in plastic surgeons' clinical practice to guide the management of patients on antithrombotic therapies, while minimizing nonessential referrals to the thrombosis service. The lack of plastic surgery-specific guidelines on this topic highlights a need for further research to "bootstrap" the risk categorization of plastic surgical procedures and their appropriate perioperative management.

摘要

鉴于人口老龄化,整形外科医生在为接受择期手术且正在接受抗血栓治疗的患者平衡手术出血风险与血栓栓塞风险方面面临着越来越大的挑战。在这一人群中,指南建议仍不明确,这导致了临床实践的异质性。我们提出了一种实用方法,总结了指南建议,以促进对已经在服用抗血栓药物的手术患者进行围手术期管理。由于缺乏整形外科的具体指南,建议主要改编自2022年美国胸科医师学会关于抗血栓治疗围手术期管理的指南,因为这些指南被认为具有权威性且在临床实践中广泛使用。基于现有的指南改编了一个临床实践概念框架,将决策分为三个步骤:(1)评估手术出血风险;(2)评估患者的血栓栓塞风险;(3)根据抗血栓药物类型确定适当的管理方法。针对继续、停用和桥接抗凝剂及抗血小板药物提供了具体指征,以及与心脏病专家或血液科医生会诊的指征。本框架可在整形外科医生的临床实践中实施,以指导对抗血栓治疗患者的管理,同时尽量减少不必要的血栓形成服务转诊。关于这一主题缺乏整形外科的具体指南,凸显了进一步研究以“引导”整形外科手术的风险分类及其适当围手术期管理的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59d2/11562235/e9b336c3370a/10.1177_22925503241256654-fig1.jpg

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