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所有患者的经皮冠状动脉介入治疗结果:一家科威特独立医疗机构的经验。

Outcomes of PCI of all comers: the experience of a Kuwaiti independent healthcare institution.

作者信息

Mudawi Telal, Alenezi Waleed, Amin Ahmed, Besada Dalia, Aly Asmaa, Fathi Assem, Al-Khdair Darar, Al-Anbaei Muath

机构信息

Consultant Interventional Cardiologist.

Cardiology Registrar.

出版信息

Br J Cardiol. 2024 Apr 16;31(2):016. doi: 10.5837/bjc.2024.016. eCollection 2024.

Abstract

We present the cumulative percutaneous coronary intervention (PCI) data of all comers (stable angina and acute coronary syndromes [ACS]) who presented to Hadi Clinic between January 2018 and December 2020. As a low-volume PCI centre in the Middle East, we wanted to find out if the outcomes of our PCI procedures are different from those of high-volume PCI centres in the UK and the Western world. Prospectively collected data of all comers for PCI (urgent and elective) were retrospectively analysed. Preprocedural data included patients' baseline characteristics (age, gender, clinical presentation and comorbidities). Intra-procedural data included access route, coronary anatomy, lesion complexity, number of stents deployed, door-to-balloon time for primary PCI, and any intraprocedural complications. Postprocedural data included average length of in-hospital stay, intra-hospital morbidity and mortality, and mortality or admission with ACS 12-36 months after the index procedure. A total of 567 patients underwent coronary catheterisation for the three-year period between January 2018 and December 2020. Mean age was 60.9 ± 9.4 years, and 459/567 (81.0%) were male. Comorbidities included dyslipidaemia 515/567 (90.9%), hypertension 460/567 (81.2%), diabetes 346/567 (61%), known prior coronary disease 250/567 (44.2%), and smoking 188/567 (33.1%). Clinical presentation was stable angina 130/567 (22.9%), non-ST-elevation acute coronary syndrome (NSTEACS) 312/567 (55%), ST-elevation myocardial infarction (STEMI) 125/567 (22.0%), and STEMI with cardiogenic shock 13/125 (10.4%). The radial approach was used in 544/567 (95.94%), the average SYNTAX score was 34.8 ± 9.6, and the average number of stents 2.6. The total number of PCI was 367 (122.3 annually) with PCI procedural complete success in 349/367 (95.1%), partial success 5/367 (1.36%), PCI procedural complications 3/367 (0.82%), PCI in-hospital mortality 1/367 (0.27%), door-to-balloon time for primary PCI 31.8 ± 12.2 minutes, subsequent admission with ACS after 12-36 months 2/367 (0.54%), and post-discharge mortality after 12-36 months 1/367 (0.27%). In conclusion, our patient population have more comorbidities and more complex coronary disease in comparison to their western counterparts. Our annual PCI numbers have been significantly lower than the recommended 400 minimum cut-off figure, yet we have achieved comparable outcomes to those of larger institutions of the western world.

摘要

我们呈现了2018年1月至2020年12月期间在哈迪诊所就诊的所有患者(稳定型心绞痛和急性冠状动脉综合征[ACS])的经皮冠状动脉介入治疗(PCI)累积数据。作为中东地区一个低手术量的PCI中心,我们想了解我们的PCI手术结果是否与英国及西方世界高手术量的PCI中心不同。对前瞻性收集的所有接受PCI治疗患者(急诊和择期)的数据进行回顾性分析。术前数据包括患者的基线特征(年龄、性别、临床表现和合并症)。术中数据包括入路途径、冠状动脉解剖结构、病变复杂性、置入支架数量、首次PCI的门球时间以及任何术中并发症。术后数据包括住院平均时长、院内发病率和死亡率,以及首次手术后12至36个月因ACS导致的死亡率或再次入院情况。在2018年1月至2020年12月的三年期间,共有567例患者接受了冠状动脉造影。平均年龄为60.9±9.4岁,459/567(81.0%)为男性。合并症包括血脂异常515/567(90.9%)、高血压460/567(81.2%)、糖尿病346/567(61%)、已知既往冠心病250/567(44.2%)以及吸烟188/567(33.1%)。临床表现为稳定型心绞痛130/567(22.9%)、非ST段抬高型急性冠状动脉综合征(NSTEACS)312/567(55%)、ST段抬高型心肌梗死(STEMI)125/567(22.0%)以及合并心源性休克的STEMI 13/125(10.4%)。544/567(95.94%)采用桡动脉入路,平均SYNTAX评分为34.8±9.6,平均置入支架数量为2.6个。PCI总数为367例(每年122.3例),PCI手术完全成功率为349/367(95.1%),部分成功率为5/367(1.36%),PCI手术并发症为3/367(0.82%),PCI院内死亡率为1/367(0.27%),首次PCI的门球时间为31.8±12.2分钟,12至36个月后因ACS再次入院率为2/367(0.54%),出院后12至36个月死亡率为1/367(

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