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1996年至2023年不列颠哥伦比亚省的牙科抗生素使用情况:我们是在倒退吗?

Dental antibiotic use in British Columbia from 1996 through 2023: Are we backsliding?

作者信息

Stenlund Säde, Huynh Jeremy, Pau Clifford, Chuang Erica, Lishman Hannah, Patrick David M

出版信息

J Am Dent Assoc. 2025 Jan;156(1):37-45.e7. doi: 10.1016/j.adaj.2024.10.001. Epub 2024 Nov 18.

Abstract

BACKGROUND

Dentists in the United States and Canada have higher rates of prescribing broad-spectrum spectrum antibiotics than dentists in some other Western countries. The authors provide an overview of dental antibiotic prescribing trends from British Columbia, Canada.

METHODS

The data include all prescriptions filed from pharmacies in British Columbia from 1996 through 2023. Dental antibiotic prescribing trends were explored visually and stratified according to patient-related characteristics, type of health service area, type of antibiotic, duration of therapy, and dentist's experience. Interrupted time series regression analysis was conducted to investigate the impact of the COVID-19 pandemic on dental antibiotic prescribing.

RESULTS

Dentistry accounted for an increasing proportion of overall antibiotic consumption in British Columbia. Dental prescriptions increased to a peak rate during the COVID-19 pandemic and remained elevated into 2023. The median duration of prescription converged toward a 7-day supply during the study period.

CONCLUSIONS

The authors documented how a decreasing trend in dental antibiotic prescribing prepandemic has been interrupted by means of continuously high rates after that event.

PRACTICAL IMPLICATIONS

Renewed efforts to ensure appropriateness of dental antibiotic prescribing are needed.

摘要

背景

美国和加拿大的牙医开具广谱抗生素的比例高于其他一些西方国家的牙医。作者概述了加拿大不列颠哥伦比亚省的牙科抗生素处方趋势。

方法

数据包括1996年至2023年不列颠哥伦比亚省各药房提交的所有处方。通过可视化方式探索牙科抗生素处方趋势,并根据患者相关特征、医疗服务区类型、抗生素类型、治疗持续时间和牙医经验进行分层。进行中断时间序列回归分析以调查新冠疫情对牙科抗生素处方的影响。

结果

在不列颠哥伦比亚省,牙科抗生素在总体抗生素消费中所占比例不断增加。牙科处方在新冠疫情期间增至峰值,并持续到2023年仍居高不下。在研究期间,处方的中位持续时间趋向于7天的供应量。

结论

作者记录了疫情前牙科抗生素处方的下降趋势如何在疫情后因持续的高处方率而中断。

实际意义

需要重新努力确保牙科抗生素处方的合理性。

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