Ketvel Laila, Vuoksimaa Eero, Pulkkinen Lea, Rose Richard J, Vedenkannas Ulla, Rapeli Pekka, Raevuori Anu, Latvala Antti
Department of Psychiatry, Division of Digital and Psychosocial Treatments, Helsinki University Hospital.
Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki.
Neuropsychology. 2025 Jan;39(1):16-27. doi: 10.1037/neu0000983. Epub 2024 Nov 18.
To investigate associations of executive function (EF) performance in adolescence with dimensional symptoms of inattention and hyperactivity-impulsivity assessed by multiple informants as well as ADHD (attention-deficit/hyperactivity disorder) symptoms based on the criteria, and whether familial factors and co-occurring symptoms of depressive disorder and conduct disorder explain these associations in a population-based sample.
In 14-year-old twins from the population-based FinnTwin12 study ( = 638-1,227), we assessed EF with commonly used neuropsychological tests. symptoms of ADHD and psychiatric disorders were assessed with a semistructured interview, and dimensional symptoms of inattention and hyperactivity-impulsivity with behavioral ratings made by the twins, their co-twins, and teachers at age 14, and by parents and teachers at age 12, the latter being different from those at age 14.
Teacher-rated inattention had the strongest association with poorer EF performance across two measurement points with different teachers; these associations were not affected by adding symptoms of depressive disorder and conduct disorder as covariates. Within-pair analyses suggested that the associations of inattention and hyperactivity-impulsivity with EF were partly explained by familial factors.
Even at a subclinical level in a sample of adolescents representing general population, ADHD symptoms are associated with EF performance. Teachers' evaluations appear especially valuable when assessing adolescents' ADHD symptoms. Our findings support the notion of dimensional ADHD symptoms in the population. (PsycInfo Database Record (c) 2025 APA, all rights reserved).
在一个基于人群的样本中，研究青少年执行功能（EF）表现与多渠道评估的注意力不集中和多动冲动维度症状以及基于标准的注意缺陷多动障碍（ADHD）症状之间的关联，以及家庭因素、抑郁症和品行障碍的共病症状是否能解释这些关联。
在基于人群的芬兰双胞胎12研究中的14岁双胞胎（n = 638 - 1227）中，我们使用常用的神经心理学测试评估执行功能。ADHD和精神障碍症状通过半结构化访谈进行评估，注意力不集中和多动冲动维度症状通过双胞胎、其同胞双胞胎以及14岁时的教师，以及12岁时的父母和教师进行的行为评分来评估，12岁时的评分者与14岁时不同。
在两个由不同教师进行测量的时间点上，教师评定的注意力不集中与较差的执行功能表现关联最强；将抑郁症和品行障碍症状作为协变量纳入后，这些关联不受影响。配对分析表明，注意力不集中和多动冲动与执行功能的关联部分可由家庭因素解释。
即使在代表普通人群的青少年样本的亚临床水平上，ADHD症状也与执行功能表现相关。在评估青少年的ADHD症状时，教师的评估似乎特别有价值。我们的研究结果支持人群中ADHD症状维度的概念。（PsycInfo数据库记录（c）2025美国心理学会，保留所有权利）
