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偶然发现一例基于胸膜的神经鞘瘤。

An incidental finding of a pleural based schwannoma.

作者信息

Griffin William, Srinivasan Nina Mac Auley, Fabre Aurelie, Healy David

机构信息

Department of Respiratory Medicine St. Vincent's University Hospital Dublin Ireland.

Department of Pathology St. Vincent's University Hospital Dublin Ireland.

出版信息

Respirol Case Rep. 2024 Nov 18;12(11):e70066. doi: 10.1002/rcr2.70066. eCollection 2024 Nov.

DOI:10.1002/rcr2.70066
PMID:39558963
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11570798/
Abstract

A man in his 40s was incidentally found to have a large right sided apical pleural based mass on imaging. This was further investigated with a CT-guided biopsy. Histological and immunohistochemical analysis of the tissue revealed a diagnosis of a Schwannoma: a rare, slow-growing benign nerve sheath tumour. Only a handful of pleural based Schwannomas have been documented in the literature. They account for about 0.2% of lung tumours. The patient was referred to cardiothoracic surgery who advised surgical resection of the mass, which he is awaiting. Here, we report a rare case of a pleural based Schwannoma which was diagnosed incidentally on chest x-ray.

摘要

一名40多岁的男性在影像学检查中偶然发现右侧肺尖部有一个较大的胸膜下肿块。通过CT引导下活检对其进行了进一步检查。对该组织进行的组织学和免疫组化分析显示诊断为神经鞘瘤:一种罕见的、生长缓慢的良性神经鞘肿瘤。文献中仅记载了少数胸膜下神经鞘瘤病例。它们约占肺肿瘤的0.2%。该患者被转诊至心胸外科,医生建议手术切除肿块,他正在等待手术。在此,我们报告一例罕见的胸膜下神经鞘瘤病例,该病例是在胸部X光检查时偶然发现的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0fe/11570798/b6a5053d8f2e/RCR2-12-e70066-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0fe/11570798/8e1e00a2163c/RCR2-12-e70066-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0fe/11570798/b6a5053d8f2e/RCR2-12-e70066-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0fe/11570798/8e1e00a2163c/RCR2-12-e70066-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0fe/11570798/b6a5053d8f2e/RCR2-12-e70066-g001.jpg

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本文引用的文献

1
Pleural Schwannoma Presenting As Musculoskeletal Type Pain: A Case Report.表现为肌肉骨骼型疼痛的胸膜神经鞘瘤:一例报告
Cureus. 2023 Apr 18;15(4):e37771. doi: 10.7759/cureus.37771. eCollection 2023 Apr.
2
Intrathoracic neurogenic tumors (ITNs): Management of solid and cystic lesions.胸腔内神经源性肿瘤(ITNs):实性和囊性病变的处理。
Thorac Cancer. 2023 Jul;14(19):1824-1830. doi: 10.1111/1759-7714.14927. Epub 2023 May 18.
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Lung schwannomas, an unusual entity: A series of five cases.肺神经鞘瘤:一种罕见的疾病——5例病例系列报道
Lung India. 2023 Jan-Feb;40(1):70-74. doi: 10.4103/lungindia.lungindia_197_22.
4
Difficulty Breathing or Just a Case of the Nerves? Incidental Finding of Primary Pleural Schwannoma in a COVID-19 Survivor.呼吸困难还是只是紧张所致?一名新冠病毒肺炎幸存者偶然发现原发性胸膜神经鞘瘤
Cureus. 2021 Aug 27;13(8):e17511. doi: 10.7759/cureus.17511. eCollection 2021 Aug.
5
Typical 22q11.2 deletion syndrome appears to confer a reduced risk of schwannoma.典型的 22q11.2 缺失综合征似乎降低了神经鞘瘤的风险。
Genet Med. 2021 Sep;23(9):1779-1782. doi: 10.1038/s41436-021-01175-0. Epub 2021 Apr 20.
6
Clamshell thoracotomy: a unique approach to a massive intrathoracic schwannoma.蛤壳式开胸术:治疗巨大胸腔神经鞘瘤的独特方法。
Ann Thorac Surg. 2011 Jan;91(1):298-301. doi: 10.1016/j.athoracsur.2010.06.054.