Salim Iffah, Mohd Saad Mohd Sazafi, Ahmad Kailani Abdul Azim Al-Abrar, Md Daud Mohd Khairi
Department of Otorhinolaryngology-Head and Neck Surgery, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, Kelantan 16150 Malaysia.
Department of Otorhinolaryngology-Head and Neck Surgery, Hospital Sungai Buloh, Sungai Buloh, 47000 Malaysia.
Indian J Otolaryngol Head Neck Surg. 2024 Dec;76(6):6009-6012. doi: 10.1007/s12070-024-05054-3. Epub 2024 Sep 17.
Skull base osteomyelitis (SBO) is a rare and lethal infection of temporal bone, uncommonly caused by purulent otitis media. Although uncommon, a young and immunocompetent person is not exceptional to develop SBO as in our case. We reported a case of SBO in a young, immunocompetent gentleman who presented with right otorrhea associated with fever, trismus, headache, and neck stiffness, which was unresponsive to oral and topical antibiotics. Examination revealed fullness at the right mastoid tip with no evidence of mastoid abscess, trismus, with restrictions of neck movements. Otoscopy of right ear showed mucopus with 10% anterosuperior tympanic membrane perforation without keratin or granulation tissue. Pus for culture and sensitivity grew and computed tomography (CT) showed osteomyelitic changes with associated parapharyngeal collection. The patient was started on intravenous antimicrobial therapy and responded well to the treatment.
颅底骨髓炎(SBO)是一种罕见的颞骨致命感染,很少由化脓性中耳炎引起。虽然不常见,但如我们的病例所示,年轻且免疫功能正常的人患SBO也并非例外。我们报告了一例年轻、免疫功能正常的男性SBO病例,该患者表现为右耳流脓伴发热、牙关紧闭、头痛和颈部僵硬,口服和局部使用抗生素均无效。检查发现右乳突尖饱满,无乳突脓肿迹象,牙关紧闭,颈部活动受限。右耳耳镜检查显示有黏液脓性分泌物,鼓膜前上10%穿孔,无角质或肉芽组织。培养及药敏试验的脓液生长情况以及计算机断层扫描(CT)显示有骨髓炎改变并伴有咽旁积脓。患者开始接受静脉抗菌治疗,治疗反应良好。