Kalra Vijay, Sharma Sudeep, Goel Nidhi, Khokhar Monika, Bhargava Aditya, Garg Parul, Jindal Nitin
Department of Otorhinolaryngology, PGIMS Rohtak, Rohtak, India.
Department of Microbiology, PGIMS Rohtak, Rohtak, India.
Indian J Otolaryngol Head Neck Surg. 2024 Dec;76(6):5666-5671. doi: 10.1007/s12070-024-05058-z. Epub 2024 Sep 10.
To identify and know the antimicrobial sensitivities of the aerobic bacteria in patients with acute otitis externa (AOE).
Sixty-six patients of acute otitis externa were prospectively analysed at a tertiary care centre in North-India from May 2021 to April 2022. Samples for culture and sensitivity were sent to the microbiology department and the results analysed.
A total of 50 samples yielded positive results for bacterial cultures. The gram-negative isolates were 60%, and the gram-positive were 40%. was the most common organism isolated overall (48%), followed by (36%). isolates were found to be most susceptible to piperacillin + tazobactam and imipenem (100%), followed by cefepime (91.67%) and ciprofloxacin (87.5%) while the isolates were found to be most susceptible to linezolid (100%) and doxycycline (94.44%), followed by clindamycin (88.89%).
Causes of bacterial diversity and their varied anti-microbial sensitivities and increasing antimicrobial resistance due to inadvertent use of antibiotics over time has caused change in susceptibility of bacteria. It therefore becomes essential to periodically assess the microbiological flora so as to provide quality and cost-effective treatment to the patient population presenting with AOE.
鉴定并了解急性外耳道炎（AOE）患者需氧菌的抗菌敏感性。
2021年5月至2022年4月，在印度北部的一家三级医疗中心对66例急性外耳道炎患者进行前瞻性分析。将培养和药敏样本送至微生物科并分析结果。
共50份样本细菌培养呈阳性。革兰氏阴性菌分离株占60%，革兰氏阳性菌占40%。总体上，[未提及的细菌名称1]是最常分离出的菌种（48%），其次是[未提及的细菌名称2]（36%）。[未提及的细菌名称1]分离株对哌拉西林+他唑巴坦和亚胺培南最敏感（100%），其次是头孢吡肟（91.67%）和环丙沙星（�7.5%），而[未提及的细菌名称2]分离株对利奈唑胺（100%）和强力霉素（94.44%）最敏感，其次是克林霉素（88.89%）。
细菌多样性的原因、其不同的抗菌敏感性以及随着时间推移因不经意使用抗生素导致的抗菌耐药性增加，已引起细菌敏感性的变化。因此，定期评估微生物菌群对于为患有急性外耳道炎的患者群体提供优质且具成本效益的治疗至关重要。
