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血清阴性抗磷脂综合征：一例具有挑战性的病例报告。

Seronegative Antiphospholipid Syndrome: A Challenging Case Report.

作者信息

Subahi Eihab A, Aboukhalaf Soha, Mohammedain Shahd, Sayed Sagda, Ali Elrazi A, Subahi Mohamed, Kamal Ijaz

机构信息

Department of General Internal Medicine Hamad Medical Corporation Doha Qatar.

Department of Radiology Hamad Medical Corporation Doha Qatar.

出版信息

Clin Case Rep. 2024 Nov 17;12(11):e9585. doi: 10.1002/ccr3.9585. eCollection 2024 Nov.

DOI:10.1002/ccr3.9585
PMID:39559286
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11570415/
Abstract

Seronegative antiphospholipid syndrome (SN-APS) is uncommon and challenging condition, which should be included in the differential diagnosis of stroke in young, since it can result in arterial thrombosis.SN-APS is typically diagnosed by exclusion; however, it is crucial to recognize it in order to choose the best antithrombotic treatment to lower the recurrence rate.

摘要

血清阴性抗磷脂综合征（SN-APS）是一种罕见且具有挑战性的病症，鉴于其可导致动脉血栓形成，在年轻患者卒中的鉴别诊断中应考虑该病。SN-APS通常通过排除法诊断；然而，识别该病症对于选择最佳抗血栓治疗以降低复发率至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/80c28778627b/CCR3-12-e9585-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/2b9997f7bf37/CCR3-12-e9585-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/af7c9eeaf782/CCR3-12-e9585-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/e02b9f594771/CCR3-12-e9585-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/91e11b265d92/CCR3-12-e9585-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/539515125bd7/CCR3-12-e9585-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/cffce4f8a383/CCR3-12-e9585-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/7e590a3755a5/CCR3-12-e9585-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/ecaa5262d405/CCR3-12-e9585-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/80c28778627b/CCR3-12-e9585-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/2b9997f7bf37/CCR3-12-e9585-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/af7c9eeaf782/CCR3-12-e9585-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/e02b9f594771/CCR3-12-e9585-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/91e11b265d92/CCR3-12-e9585-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/539515125bd7/CCR3-12-e9585-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/cffce4f8a383/CCR3-12-e9585-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/7e590a3755a5/CCR3-12-e9585-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/ecaa5262d405/CCR3-12-e9585-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ea/11570415/80c28778627b/CCR3-12-e9585-g001.jpg

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本文引用的文献

1
Seronegative Obstetric Antiphospholipid Syndrome Finally Treated Successfully.血清阴性产科抗磷脂综合征最终成功治愈。
Eur J Case Rep Intern Med. 2022 Dec 5;9(12):003686. doi: 10.12890/2022_003686. eCollection 2022.
2
Recurrent Cerebral Artery Dissection Associated with Seronegative Antiphospholipid Antibody Syndrome.复发性脑动脉夹层与血清阴性抗磷脂抗体综合征相关
Tomography. 2022 Mar 10;8(2):754-759. doi: 10.3390/tomography8020062.
3
Seronegative antiphospholipid syndrome: refining the value of "non-criteria" antibodies for diagnosis and clinical management.
抗磷脂抗体阴性的抗磷脂综合征：为诊断和临床管理“非标准”抗体赋值。
Haematologica. 2020 Mar;105(3):562-572. doi: 10.3324/haematol.2019.221945. Epub 2020 Jan 30.
4
Management of thrombotic and obstetric antiphospholipid syndrome: a systematic literature review informing the EULAR recommendations for the management of antiphospholipid syndrome in adults.抗磷脂抗体综合征血栓形成与产科表现的管理：系统文献回顾为 EULAR 成人抗磷脂综合征管理建议提供依据
RMD Open. 2019 Apr 28;5(1):e000924. doi: 10.1136/rmdopen-2019-000924. eCollection 2019.
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First-trimester low-dose prednisolone in refractory antiphospholipid antibody-related pregnancy loss.早孕期小剂量泼尼松治疗难治性抗磷脂抗体相关复发性流产。
Blood. 2011 Jun 23;117(25):6948-51. doi: 10.1182/blood-2011-02-339234. Epub 2011 Apr 28.
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Seronegative antiphospholipid syndrome.血清阴性抗磷脂综合征
Ann Rheum Dis. 2003 Dec;62(12):1127. doi: 10.1136/ard.2003.006163.