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番木瓜叶提取物是治疗登革热引起的血小板减少症的良方吗?

Is Papaya Leaf Extract the Sweet Remedy for Dengue-Induced Thrombocytopenia?

作者信息

Jaggernauth Sheneel, Ramoutar Shyam R, Ramoutar Renuka, Piaralal Neiala

机构信息

Department of Medicine, Eric Williams Medical Sciences Complex, Champ Fleurs, TTO.

Department of Opthalmology, Eric Williams Medical Sciences Complex, Champ Fleurs, TTO.

出版信息

Cureus. 2024 Oct 19;16(10):e71852. doi: 10.7759/cureus.71852. eCollection 2024 Oct.

Abstract

Dengue fever, caused by the dengue virus and transmitted by , poses a significant health challenge in tropical regions like Trinidad and Tobago, with severe cases leading to life-threatening complications. This case study presents a 65-year-old female with dengue exhibiting warning signs, characterized by persistent fever, abdominal pain, and thrombocytopenia. Despite supportive care, including intravenous fluids and symptomatic treatment, her platelet count remained critically low at 12.1 x 10/L. Following the introduction of diluted papaya leaf extract into her treatment regimen, her platelet count significantly improved to 122.7 x 10/L within two days, eventually returning to normal at follow-up appointments. This case suggests that Carica papaya leaf extract may provide therapeutic benefits in boosting platelet counts in dengue patients when used alongside conventional supportive care. Further research is essential to understand the extent of papaya's benefits and to integrate it safely into dengue management practices, potentially enhancing treatment options for affected individuals. In addition, public health efforts should be prioritized in raising awareness about dengue prevention, early diagnosis, and effective management strategies to reduce the disease's impact in affected regions.

摘要

登革热由登革病毒引起,通过[此处原文缺失传播媒介相关内容]传播,在特立尼达和多巴哥等热带地区构成重大的健康挑战,严重病例会导致危及生命的并发症。本病例研究介绍了一名65岁患有登革热且出现警示症状的女性,其症状表现为持续发热、腹痛和血小板减少。尽管采取了包括静脉输液和对症治疗在内的支持性护理措施,她的血小板计数仍极低,为12.1×10⁹/L。在其治疗方案中引入稀释的番木瓜叶提取物后,她的血小板计数在两天内显著提高至122.7×10⁹/L,在后续随访时最终恢复正常。该病例表明,番木瓜叶提取物与传统支持性护理措施一起使用时,可能对提高登革热患者的血小板计数具有治疗益处。进一步的研究对于了解番木瓜的益处程度以及将其安全地纳入登革热管理实践至关重要,这有可能增加对受影响个体的治疗选择。此外,应优先开展公共卫生工作,提高对登革热预防、早期诊断和有效管理策略的认识,以减少该疾病在受影响地区的影响。

相似文献

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Dengue Fever: Therapeutic Potential of L. Leaves.登革热:L. 叶的治疗潜力
Front Pharmacol. 2021 Apr 26;12:610912. doi: 10.3389/fphar.2021.610912. eCollection 2021.

本文引用的文献

1
Leaf Juice for Dengue: A Scoping Review.叶汁治疗登革热:范围综述。
Nutrients. 2022 Apr 11;14(8):1584. doi: 10.3390/nu14081584.
2
The Future of Leaf Extract as an Herbal Medicine Product.叶提取物作为草药产品的未来。
Molecules. 2021 Nov 17;26(22):6922. doi: 10.3390/molecules26226922.

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