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一名74岁男性的天然瓣膜军团菌性心内膜炎:病例报告与文献复习

Native Valve Legionella Endocarditis in a 74-Year-Old Male: A Case Report and Review.

作者信息

Porter Angelina A, Abro Anthony, Desai Nisha, Yazdani Habeeb

机构信息

Internal Medicine, Ascension Health, Warren, USA.

Internal Medicine, Ascension St. John Hospital, Warren, USA.

出版信息

Cureus. 2024 Oct 19;16(10):e71870. doi: 10.7759/cureus.71870. eCollection 2024 Oct.

DOI:10.7759/cureus.71870
PMID:39559678
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11572955/
Abstract

Legionella is a bacterium that primarily causes respiratory infections. Rarely, it can result in extrapulmonary infections like endocarditis. We present a case of native valve endocarditis caused by Legionella in a 74-year-old male. Our patient initially presented with fever, fatigue, confusion, moderate cough, and dysuria. Subsequent presentation included atrial fibrillation and pulmonary infiltrates on chest X-ray. His clinical sequelae and positive urine Legionella antigen prompted treatment with antibiotics and cardiac medication. Echocardiograms revealed vegetation on the mitral valve leaflet suggestive of endocarditis. The patient improved after appropriate antibiotic and anti-arrhythmic therapy. In presenting this case and literature review, we emphasize the importance of considering atypical pathogens in common clinical presentations.

摘要

嗜肺军团菌是一种主要引起呼吸道感染的细菌。极少情况下,它可导致心内膜炎等肺外感染。我们报告一例74岁男性由嗜肺军团菌引起的自身瓣膜心内膜炎病例。我们的患者最初表现为发热、乏力、意识模糊、中度咳嗽和排尿困难。随后的表现包括心房颤动和胸部X光显示的肺部浸润。他的临床后遗症及尿嗜肺军团菌抗原阳性促使给予抗生素和心脏药物治疗。超声心动图显示二尖瓣叶上有赘生物,提示心内膜炎。经过适当的抗生素和抗心律失常治疗后,患者病情好转。在报告此病例并进行文献综述时,我们强调在常见临床表现中考虑非典型病原体的重要性。

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本文引用的文献

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Expect the unexpected: endocarditis caused by Legionella feeleii.意料之外:嗜肺军团菌引起的心内膜炎。
Lab Med. 2024 Nov 4;55(6):791-794. doi: 10.1093/labmed/lmae029.
2
Updates in Culture-Negative Endocarditis.血培养阴性的心内膜炎的进展
Pathogens. 2023 Aug 10;12(8):1027. doi: 10.3390/pathogens12081027.
3
Case report: A prosthetic valve endocarditis caused by in an immunocompetent patient.病例报告:一名免疫功能正常的患者发生了由[未提及具体病因]引起的人工瓣膜心内膜炎。
Front Med (Lausanne). 2022 Nov 3;9:1055465. doi: 10.3389/fmed.2022.1055465. eCollection 2022.
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Legionella endocarditis: A case report and review.军团菌性心内膜炎:一例报告并文献复习。
Enferm Infecc Microbiol Clin (Engl Ed). 2022 Apr;40(4):190-194. doi: 10.1016/j.eimce.2020.10.013.
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Prosthetic Valve Legionella Endocarditis.人工瓣膜莱姆心内膜炎。
Ann Thorac Surg. 2019 Oct;108(4):e271-e272. doi: 10.1016/j.athoracsur.2019.02.006. Epub 2019 Mar 14.
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Legionnaire's Disease: Cardiac Manifestations.军团病:心脏表现
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Am J Cardiol. 2016 Feb 1;117(3):427-33. doi: 10.1016/j.amjcard.2015.11.012. Epub 2015 Nov 18.
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New Microbes New Infect. 2015 Oct 22;8:113-5. doi: 10.1016/j.nmni.2015.10.003. eCollection 2015 Nov.
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