Heart and Thoracic Surgery, Heart Center, Kuopio University Hospital, Kuopio, Finland.
Vascular Surgery, Surgery Clinic, Central Hospital of North Karelia, Joensuu, Finland.
Scand Cardiovasc J. 2024 Dec;58(1):2430001. doi: 10.1080/14017431.2024.2430001. Epub 2024 Nov 19.
Current guidelines recommend that surveillance imaging should be performed at least every third year for patients with ascending thoracic aortic aneurysm (ATAA) even though such aneurysms' growth rate is mostly minimal. The purpose of this study was to clarify the pattern of the growth of ATAAs in a real-life patient population to adjust the optimal timing of aortic surveillance for each patient. This study includes patients ( = 209) who had been followed due to ATAA in the central hospital of North Karelia in Eastern Finland between years 2007 and 2023. Aortic imaging was performed using either computed tomography (CT) or transthoracic echocardiography (TTE). In the CT images, the aortic dimensions were measured according to guidelines in four levels of the ascending aorta. TTE measurements were collected from medical records. Measurements were used to explore the pattern of the ATAA growth. During the mean surveillance time 5.0 ± 3.5 years, the median growth rate of ATAAs was 0.37 mm/year. One fifth (21.5%) of the aneurysms showed no expansion during the follow-up. Despite the minimal growth rate during surveillance, some patients ended up exceeding the cut-off for preventive surgery. Among the patients, who showed expansion during the follow-up, the linear model seemed to best describe the growth of ATAA. The majority of the patients had a very low ATAA growth rate. Based on this study, the growth of ATAAs could be described using a linear model, which could, in turn, be used to predict the growth of an aneurysm.
目前的指南建议,即使升主动脉瘤(ATAA)的生长速度大多很小,也应至少每 3 年对患者进行一次监测成像。本研究的目的是阐明真实患者人群中 ATAA 的生长模式,以调整每位患者主动脉监测的最佳时机。本研究包括 2007 年至 2023 年间在芬兰东部北卡累利阿中心医院因 ATAA 而接受随访的患者(n=209)。主动脉成像使用计算机断层扫描(CT)或经胸超声心动图(TTE)进行。在 CT 图像中,根据指南在升主动脉的四个水平测量主动脉尺寸。TTE 测量值从病历中收集。测量值用于探索 ATAA 生长模式。在平均监测时间 5.0±3.5 年内,ATAA 的中位增长率为 0.37mm/年。五分之一(21.5%)的动脉瘤在随访期间没有扩张。尽管在监测期间生长速度很小,但一些患者最终超过了预防性手术的截止值。在随访期间显示扩张的患者中,线性模型似乎最能描述 ATAA 的生长。大多数患者的 ATAA 生长速度非常低。基于这项研究,ATAA 的生长可以用线性模型来描述,这反过来又可以用于预测动脉瘤的生长。