Smales E, Perry C M, Macdonald J S, Baker J W
Clin Radiol. 1986 Jan;37(1):19-22. doi: 10.1016/s0009-9260(86)80156-8.
Lymphography has been used to evaluate the pelvic and para-aortic nodes in 205 patients with carcinoma of the cervix treated between 1970 and 1979. The incidence of positive nodes was found to be 17% for Stage I, 24% for Stage II, 52% for Stage III and 100% for Stage IV. Of 73 patients who had lymphograms before Wertheim's hysterectomy, four out of 59 patients (7%) with negative lymphograms had histologically positive nodes; four out of 14 (28%) with positive lymphograms had negative nodes. Within each FIGO stage a positive lymphogram indicated a poor prognosis. The actuarial 5-year survival rates for patients with negative and positive lymphograms were 94% and 55% respectively for Stage I, 72% and 64% for Stage II, and 34% and 17% for Stage III. Of 39 patients with positive lymphograms who died of tumour, 31 out of 39 (80%) had distant metastases, compared with nine out of 29 patients (31%) with negative lymphograms. It is concluded that lymphography is a valuable method of evaluating lymph node status in carcinoma of the cervix.
淋巴造影术已被用于评估1970年至1979年间接受治疗的205例宫颈癌患者的盆腔和腹主动脉旁淋巴结。发现I期患者淋巴结阳性发生率为17%,II期为24%,III期为52%,IV期为100%。在73例接受韦特海姆子宫切除术前行淋巴造影的患者中,59例淋巴造影阴性患者中有4例(7%)组织学检查发现淋巴结阳性;14例淋巴造影阳性患者中有4例(28%)淋巴结阴性。在国际妇产科联合会(FIGO)各期内,淋巴造影阳性提示预后不良。I期淋巴造影阴性和阳性患者的5年精算生存率分别为94%和55%,II期为72%和64%,III期为34%和17%。在39例因肿瘤死亡的淋巴造影阳性患者中,39例中有31例(80%)发生远处转移,而29例淋巴造影阴性患者中有9例(31%)发生远处转移。结论是,淋巴造影术是评估宫颈癌淋巴结状态的一种有价值的方法。