两种变温动物在体内不同温度下合成的胶原蛋白的脯氨酸羟基化作用。

Proline hydroxylation of collagens synthesized at different temperatures in vivo by two poikilothermic species.

作者信息

Cohen-Solal L, Castanet J, Meunier F J, Glimcher M J

出版信息

Comp Biochem Physiol B. 1986;83(2):483-6. doi: 10.1016/0305-0491(86)90399-8.

Abstract

Extent of prolyl hydroxylation in newly synthesized viper collagen is decreased at 10 degrees C to approximately 23% of normal on skin and to approximately 57% of normal in bone collagen. At 20 degrees C, prolyl hydroxylation is approximately 50% of normal in skin and normal in bone. At 10 degrees C and 20 degrees C, prolyl hydroxylation is decreased approximately 32% in the skin collagen of carp. In contrast, prolyl hydroxylation is unchanged at 10 and 20 degrees C in bone, scale and lepidotrichia. Prolyl hydroxylation of cartilaginous endoskeleton showed an approximately 25% decrease at 20 degrees C.

摘要

在10摄氏度时，新合成的蝰蛇胶原蛋白中脯氨酰羟化程度降低，皮肤中降至正常水平的约23%，骨胶原蛋白中降至正常水平的约57%。在20摄氏度时，皮肤中脯氨酰羟化约为正常水平的50%，骨中为正常水平。在10摄氏度和20摄氏度时，鲤鱼皮肤胶原蛋白中的脯氨酰羟化降低约32%。相比之下，在10摄氏度和20摄氏度时，骨、鳞片和鳍条中的脯氨酰羟化没有变化。软骨内骨骼的脯氨酰羟化在20摄氏度时显示约25%的降低。