• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

专家无法可靠地检测到 AI 生成的组织学数据。

Experts fail to reliably detect AI-generated histological data.

机构信息

Institute for Physiology, Faculty of Medicine, University of Freiburg, 79108, Freiburg, Germany.

BrainLinks-BrainTools, IMBIT (Institute for Machine-Brain Interfacing Technology), University of Freiburg, Georges-Köhler-Allee 201, 79110, Freiburg, Germany.

出版信息

Sci Rep. 2024 Nov 19;14(1):28677. doi: 10.1038/s41598-024-73913-8.

DOI:10.1038/s41598-024-73913-8
PMID:39562595
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11577117/
Abstract

AI-based methods to generate images have seen unprecedented advances in recent years challenging both image forensic and human perceptual capabilities. Accordingly, these methods are expected to play an increasingly important role in the fraudulent fabrication of data. This includes images with complicated intrinsic structures such as histological tissue samples, which are harder to forge manually. Here, we use stable diffusion, one of the most recent generative algorithms, to create such a set of artificial histological samples. In a large study with over 800 participants, we study the ability of human subjects to discriminate between these artificial and genuine histological images. Although they perform better than naive participants, we find that even experts fail to reliably identify fabricated data. While participant performance depends on the amount of training data used, even low quantities are sufficient to create convincing images, necessitating methods and policies to detect fabricated data in scientific publications.

摘要

基于人工智能的图像生成方法近年来取得了前所未有的进展,这不仅对图像取证技术提出了挑战,也对人类的感知能力提出了挑战。因此,这些方法有望在数据的欺诈性伪造中发挥越来越重要的作用。这包括具有复杂内在结构的图像,如组织学样本,这些图像更难手动伪造。在这里,我们使用最先进的生成算法之一——稳定扩散,来创建这样一组人工组织学样本。在一项有 800 多名参与者参与的大型研究中,我们研究了人类受试者区分这些人工和真实组织学图像的能力。尽管他们的表现优于天真的参与者,但我们发现,即使是专家也无法可靠地识别伪造的数据。虽然参与者的表现取决于所使用的训练数据量,但即使是少量的数据也足以生成令人信服的图像,因此需要制定方法和政策来检测科学出版物中的伪造数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fc4/11577117/cc41cd555b1f/41598_2024_73913_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fc4/11577117/5ac81fecc4da/41598_2024_73913_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fc4/11577117/5c2e106e8ee5/41598_2024_73913_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fc4/11577117/cc41cd555b1f/41598_2024_73913_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fc4/11577117/5ac81fecc4da/41598_2024_73913_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fc4/11577117/5c2e106e8ee5/41598_2024_73913_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fc4/11577117/cc41cd555b1f/41598_2024_73913_Fig3_HTML.jpg

相似文献

1
Experts fail to reliably detect AI-generated histological data.专家无法可靠地检测到 AI 生成的组织学数据。
Sci Rep. 2024 Nov 19;14(1):28677. doi: 10.1038/s41598-024-73913-8.
2
Artificial Intelligence Can Generate Fraudulent but Authentic-Looking Scientific Medical Articles: Pandora's Box Has Been Opened.人工智能可以生成虚假但看起来真实的科学医学文章:潘多拉的盒子已经被打开。
J Med Internet Res. 2023 May 31;25:e46924. doi: 10.2196/46924.
3
Generative artificial intelligence to produce high-fidelity blastocyst-stage embryo images.生成式人工智能生成高保真囊胚期胚胎图像。
Hum Reprod. 2024 Jun 3;39(6):1197-1207. doi: 10.1093/humrep/deae064.
4
An artificial intelligence-driven scoring system to measure histological disease activity in ulcerative colitis.人工智能驱动的溃疡性结肠炎组织学疾病活动评分系统。
United European Gastroenterol J. 2024 Oct;12(8):1028-1033. doi: 10.1002/ueg2.12562. Epub 2024 Apr 8.
5
Revolutionizing Digital Pathology With the Power of Generative Artificial Intelligence and Foundation Models.利用生成式人工智能和基础模型推动数字病理学革命。
Lab Invest. 2023 Nov;103(11):100255. doi: 10.1016/j.labinv.2023.100255. Epub 2023 Sep 26.
6
AI-enabled image fraud in scientific publications.科学出版物中利用人工智能的图像造假。
Patterns (N Y). 2022 Jul 8;3(7):100511. doi: 10.1016/j.patter.2022.100511.
7
Evaluation and comparison of synthetic computed tomography algorithms with 3T MRI for prostate radiotherapy: AI-based versus bulk density method.用于前列腺放疗的合成计算机断层扫描算法与3T磁共振成像的评估和比较:基于人工智能的方法与体密度法
J Appl Clin Med Phys. 2025 Mar;26(3):e14581. doi: 10.1002/acm2.14581. Epub 2024 Nov 29.
8
Fitness for Purpose of Text-to-Image Generative Artificial Intelligence Image Creation in Medical Imaging.医学成像中基于文本到图像生成式人工智能的图像创建的适用性
J Nucl Med Technol. 2025 Mar 5;53(1):63-67. doi: 10.2967/jnmt.124.268402.
9
Gender and Ethnicity Bias of Text-to-Image Generative Artificial Intelligence in Medical Imaging, Part 1: Preliminary Evaluation.医学成像中基于文本生成图像的人工智能的性别和种族偏见,第1部分:初步评估
J Nucl Med Technol. 2024 Dec 4;52(4):356-359. doi: 10.2967/jnmt.124.268332.
10
Development of a multi-scanner facility for data acquisition for digital pathology artificial intelligence.开发用于数字病理学人工智能的数据采集的多扫描仪设施。
J Pathol. 2024 Sep;264(1):80-89. doi: 10.1002/path.6326. Epub 2024 Jul 10.

引用本文的文献

1
Image fraud in nuclear medicine research.核医学研究中的图像造假。
Eur J Nucl Med Mol Imaging. 2025 Aug 16. doi: 10.1007/s00259-025-07515-5.
2
How good are medical students and researchers in detecting duplications in digital images from research articles: a cross-sectional survey.医学生和研究人员在检测研究文章数字图像中的重复内容方面能力如何:一项横断面调查。
Res Integr Peer Rev. 2025 Aug 8;10(1):14. doi: 10.1186/s41073-025-00172-0.
3
Fake AI images will cause headaches for journals.虚假人工智能图像将给期刊带来麻烦。

本文引用的文献

1
More than 10,000 research papers were retracted in 2023 - a new record.2023年有超过1万篇研究论文被撤回,创下了新纪录。
Nature. 2023 Dec;624(7992):479-481. doi: 10.1038/d41586-023-03974-8.
2
Harnessing the power of synthetic data in healthcare: innovation, application, and privacy.利用合成数据在医疗保健领域的力量:创新、应用与隐私。
NPJ Digit Med. 2023 Oct 9;6(1):186. doi: 10.1038/s41746-023-00927-3.
3
AI intensifies fight against 'paper mills' that churn out fake research.人工智能加强了对炮制虚假研究的“论文工厂”的打击力度。
Nature. 2025 May 27. doi: 10.1038/d41586-025-01488-z.
4
AI detectors are poor western blot classifiers: a study of accuracy and predictive values.人工智能检测工具在蛋白质印迹法分类方面表现不佳:准确性和预测价值研究
PeerJ. 2025 Feb 20;13:e18988. doi: 10.7717/peerj.18988. eCollection 2025.
Nature. 2023 Jun;618(7964):222-223. doi: 10.1038/d41586-023-01780-w.
4
Deep learning generates synthetic cancer histology for explainability and education.深度学习生成合成癌症组织学图像用于可解释性研究和教育。
NPJ Precis Oncol. 2023 May 29;7(1):49. doi: 10.1038/s41698-023-00399-4.
5
A Large-scale Synthetic Pathological Dataset for Deep Learning-enabled Segmentation of Breast Cancer.用于深度学习辅助乳腺癌分割的大规模合成病理数据集。
Sci Data. 2023 Apr 21;10(1):231. doi: 10.1038/s41597-023-02125-y.
6
Synthetic data in health care: A narrative review.医疗保健中的合成数据:一篇叙述性综述。
PLOS Digit Health. 2023 Jan 6;2(1):e0000082. doi: 10.1371/journal.pdig.0000082. eCollection 2023 Jan.
7
AI-enabled image fraud in scientific publications.科学出版物中利用人工智能的图像造假。
Patterns (N Y). 2022 Jul 8;3(7):100511. doi: 10.1016/j.patter.2022.100511.
8
Deepfakes: A new threat to image fabrication in scientific publications?深度伪造:科学出版物中图像造假的新威胁?
Patterns (N Y). 2022 May 13;3(5):100509. doi: 10.1016/j.patter.2022.100509.
9
Prevalence of questionable research practices, research misconduct and their potential explanatory factors: A survey among academic researchers in The Netherlands.可疑研究行为、研究不端行为及其潜在解释因素的流行程度:荷兰学术研究人员的调查。
PLoS One. 2022 Feb 16;17(2):e0263023. doi: 10.1371/journal.pone.0263023. eCollection 2022.
10
AI-synthesized faces are indistinguishable from real faces and more trustworthy.人工智能合成的人脸与真实人脸难以区分,并且更值得信任。
Proc Natl Acad Sci U S A. 2022 Feb 22;119(8). doi: 10.1073/pnas.2120481119.