Zimmermann G, Breitfellner G, Dirschmid K, Müller G, Fritzsche H, Brändle J
Chirurg. 1986 Jan;57(1):27-30.
In view of the benign clinical course of the atypical adenoma and the high diagnostic accuracy of our frozen sections we feel that subtotal strumectomy with in toto removal of the adenoma and closely spaced follow-ups constitutes an adequate treatment of this thyroid neoplasm. In our opinion primary lobectomy means unnecessarily exposing a disproportionately high percentage of patients to the higher complication risk of this more radical surgery. From 1977 to 1982 there were 47 cases of atypical adenoma among our patients. The ratio men: women was 1:3.7, the mean age of the patients was 44 years. The patients underwent subtotal strumectomy. In the period under review "atypical adenoma" diagnosed on the basis of frozen sections turned out to be carcinoma in 5 instances. The follow-up period of the 47 patients that underwent surgery ranges from 1 1/2 to 7 years. None of the patients has had tumor regrowth so far.
鉴于非典型腺瘤的临床病程良性以及我们冰冻切片的高诊断准确性，我们认为次全甲状腺切除术并完整切除腺瘤以及密切随访构成了对这种甲状腺肿瘤的充分治疗。我们认为，一期甲状腺叶切除术意味着不必要地使相当高比例的患者面临这种更激进手术的更高并发症风险。1977年至1982年期间，我们的患者中有47例非典型腺瘤病例。男女比例为1:3.7，患者的平均年龄为44岁。这些患者接受了次全甲状腺切除术。在审查期间，基于冰冻切片诊断为“非典型腺瘤”的病例中有5例后来被证实为癌。接受手术的47例患者的随访期为1.5年至7年。到目前为止，没有患者出现肿瘤复发。
