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The effects between andexanet alpha and four-factor prothrombin complex concentrate on DOACs anticoagulation reversal.

作者信息

Yang Tengfei, Zhao Bo

机构信息

Department of Social Services, Shengjing Hospital of China Medical University, Shenyang, 110004, Liaoning Province, China.

Department of Pulmonary and Critical Care Medicine, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Heping District, Shenyang, 110004, Liaoning Province, China.

出版信息

Crit Care. 2024 Nov 19;28(1):373. doi: 10.1186/s13054-024-05157-x.

DOI:10.1186/s13054-024-05157-x
PMID:39563439
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11577887/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c4a/11577887/d2e01f433810/13054_2024_5157_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c4a/11577887/739b47bec287/13054_2024_5157_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c4a/11577887/d2e01f433810/13054_2024_5157_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c4a/11577887/739b47bec287/13054_2024_5157_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c4a/11577887/d2e01f433810/13054_2024_5157_Fig2_HTML.jpg

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本文引用的文献

1
Andexanet alpha versus four-factor prothrombin complex concentrate in DOACs anticoagulation reversal: an updated systematic review and meta-analysis.依达赛珠单抗 α 对比四种因子的凝血酶原复合物在 DOACs 抗凝逆转中的应用:一项更新的系统评价和荟萃分析。
Crit Care. 2024 Jul 5;28(1):221. doi: 10.1186/s13054-024-05014-x.
2
The use of andexanet alfa vs. 4-factor prothrombin complex concentrates in the setting of life-threatening intracranial hemorrhage.依达赛珠单抗与 4 因子凝血酶原复合物在危及生命的颅内出血中的应用比较。
Blood Coagul Fibrinolysis. 2024 Apr 1;35(3):94-100. doi: 10.1097/MBC.0000000000001279. Epub 2024 Feb 12.
3
Andexanet alfa versus non-specific treatments for intracerebral hemorrhage in patients taking factor Xa inhibitors - Individual patient data analysis of ANNEXA-4 and TICH-NOAC.
依达赛珠单抗对比非特异性治疗用于服用因子 Xa 抑制剂的颅内出血患者:ANNEXA-4 和 TICH-NOAC 的个体患者数据分析。
Int J Stroke. 2024 Jun;19(5):506-514. doi: 10.1177/17474930241230209. Epub 2024 Mar 8.
4
The use of andexanet alfa and 4-factor prothrombin complex concentrate in intracranial hemorrhage.依达赛珠单抗和 4 因子凝血酶原复合物在颅内出血中的应用。
Am J Emerg Med. 2023 Feb;64:74-77. doi: 10.1016/j.ajem.2022.11.023. Epub 2022 Nov 18.
5
Hematoma Expansion and Clinical Outcomes in Patients With Factor-Xa Inhibitor-Related Atraumatic Intracerebral Hemorrhage Treated Within the ANNEXA-4 Trial Versus Real-World Usual Care.依诺肝素相关非外伤性颅内出血患者在 ANNEXA-4 试验内接受治疗与真实世界常规治疗的血肿扩大和临床结局。
Stroke. 2022 Feb;53(2):532-543. doi: 10.1161/STROKEAHA.121.034572. Epub 2021 Oct 14.
6
Retrospective Comparison of Andexanet Alfa and 4-Factor Prothrombin Complex for Reversal of Factor Xa-Inhibitor Related Bleeding.依达赛珠单抗与 4 因子凝血酶原复合物用于逆转 Xa 因子抑制剂相关出血的回顾性比较
Clin Appl Thromb Hemost. 2021 Jan-Dec;27:10760296211039020. doi: 10.1177/10760296211039020.
7
Andexanet alfa and four-factor prothrombin complex concentrate for reversal of apixaban and rivaroxaban in patients diagnosed with intracranial hemorrhage.andexanet alfa和四因子凝血酶原复合物浓缩剂用于逆转阿哌沙班和利伐沙班在颅内出血患者中的作用。
J Thromb Thrombolysis. 2022 Jan;53(1):167-175. doi: 10.1007/s11239-021-02495-3. Epub 2021 Jun 8.