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Antiestrogen therapy in pancreatic carcinoma: a preliminary report.

作者信息

Tønnesen K, Kamp-Jensen M

出版信息

Eur J Surg Oncol. 1986 Mar;12(1):69-70.

PMID:3956756
Abstract

Ten patients with unresected pancreatic carcinoma, treated with Nolvadex 10 mg 3 times a day were compared to a historic untreated control group. The median survival was 7 months in the treated group compared to 3 months in the untreated. In the control group all patients died within the first 9 months, in the treated group 40% of the patients were still alive after 14 months.

摘要

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引用本文的文献

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Transl Gastroenterol Hepatol. 2021 Jan 5;6:9. doi: 10.21037/tgh.2020.02.16. eCollection 2021.
2
R269C variant of ESR1: high prevalence and differential function in a subset of pancreatic cancers.ESR1 基因 R269C 变异:在部分胰腺癌中高发生率及功能差异。
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Clinical significance of stromal ER and PR expression in periampullary adenocarcinoma.
壶腹周围腺癌中基质雌激素受体和孕激素受体表达的临床意义
Biomark Res. 2019 Nov 19;7:26. doi: 10.1186/s40364-019-0176-9. eCollection 2019.
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Prognosis of common cancers.
Can Fam Physician. 1990 May;36:955-9.
5
Flutamide in unresectable pancreatic adenocarcinoma: a randomized, double-blind, placebo-controlled trial.氟他胺治疗不可切除胰腺腺癌:一项随机、双盲、安慰剂对照试验
Invest New Drugs. 2006 May;24(3):189-94. doi: 10.1007/s10637-005-3536-2.
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Chemoprevention for pancreatic cancer.胰腺癌的化学预防
Int J Gastrointest Cancer. 2003;33(1):27-41. doi: 10.1385/IJGC:33:1:27.
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BMJ. 1998 Jun 27;316(7149):1935-8. doi: 10.1136/bmj.316.7149.1935.
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Treatment of pancreatic cancer. Promises and problems of tamoxifen, somatostatin analogs, and gemcitabine.胰腺癌的治疗。他莫昔芬、生长抑素类似物和吉西他滨的前景与问题。
Int J Pancreatol. 1997 Oct;22(2):81-93. doi: 10.1007/BF02787465.
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Hormonal therapy of pancreatic carcinoma. Rationale and perspectives.胰腺癌的激素治疗。原理与前景。
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10
Oophorectomy has no effect on experimental pancreatic carcinogenesis in the Syrian hamster.卵巢切除术对叙利亚仓鼠的实验性胰腺癌发生没有影响。
Br J Cancer. 1989 May;59(5):696-7. doi: 10.1038/bjc.1989.145.