体重调整后的腰围指数与心血管疾病：伊朗拉万萨尔的一项基于人群的研究。

Weight-adjusted waist index and cardiovascular disease: a population-based study in Ravansar, Iran.

作者信息

Sadafi Sepehr, Azizi Ali, Shakiba Ebrahim, Pasdar Yahya

机构信息

Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Social Development and Health Promotion Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.

出版信息

Arch Public Health. 2024 Nov 20;82(1):219. doi: 10.1186/s13690-024-01451-w.

DOI:10.1186/s13690-024-01451-w

PMID:39568057

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11577860/

Abstract

BACKGROUND

The weight-adjusted-waist index (WWI) is a relatively new index to obesity. This study aimed to explore the reationship between WWI and cardiovascular disease (CVD).

METHODS

This cross-sectional study included 8,899 participants aged 35 to 65 from the Ravansar non-communicable diseases (RaNCD) cohort study in Ravansar, Iran. The WWI was calculated by dividing waist circumference (WC) by the square root of weight. The receiver operating characteristic (ROC) curve was utilized to assess the predictive performance of WWI in relation to CVD. The study applied multiple logistic regression to assess the association between WWI and CVD.

RESULTS

Participants had an average age of 47.52 ± 8.29 years, with 45.30% being men and 41.13% residing in rural areas. The prevalence of CVD was found to be 17.36%. A positive correlation between WWI and CVD was obseved, with individuals in the highest WWI quartile having a 36% (OR = 1.36, 95%CI: 1.11, 1.78) greater odds of CVD compared to those in the lowest quartile (OR = 1.03, 95%CI: 0.79, 1.33) (ptrend = 0.010). Subgroup analyses indicated stronger links between WWI and CVD among participants over 50, males, urban residents, those of high socioeconomic status (SES), and passive smokers (p < 0.001). The ROC analysis revealed that WWI is a greater ability in predicting CVD (AUC: 0.64, 95%CI: 0.61, 0.64) compared to body mass index (BMI) (AUC: 0.60, 95%CI: 0.58, 0.61) and WC (AUC: 0.61, 95%CI: 0.59, 0.62).

CONCLUSION

The increase in WWI elevates the odds of CVD, making the management of WWI crucial for CVD prevention.

摘要

背景

体重调整腰围指数（WWI）是一种相对较新的肥胖指标。本研究旨在探讨WWI与心血管疾病（CVD）之间的关系。

方法

这项横断面研究纳入了来自伊朗拉万萨尔非传染性疾病（RaNCD）队列研究的8899名年龄在35至65岁之间的参与者。WWI通过腰围（WC）除以体重平方根来计算。采用受试者工作特征（ROC）曲线评估WWI对CVD的预测性能。该研究应用多元逻辑回归来评估WWI与CVD之间的关联。

结果

参与者的平均年龄为47.52±8.29岁，其中45.30%为男性，41.13%居住在农村地区。CVD的患病率为17.36%。观察到WWI与CVD之间存在正相关，与最低四分位数组（OR = 1.03，95%CI：0.79，1.33）相比，WWI最高四分位数组的个体患CVD的几率高36%（OR = 1.36, 95%CI：1.11, 1.78）（P趋势 = 0.010）。亚组分析表明，在50岁以上的参与者、男性、城市居民、高社会经济地位（SES）者和被动吸烟者中，WWI与CVD之间的联系更强（P < 0.001）。ROC分析显示，与体重指数（BMI）（AUC：0.60，95%CI：0.58，0.61）和WC（AUC：0.61，95%CI：0.59，0.62）相比，WWI在预测CVD方面能力更强（AUC：0.64，95%CI：0.61，0.64）。