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提高CT引导下骨活检的精准度:探索双能CT成像的潜力。

Advancing precision in CT-guided bone biopsies: exploring the potential of dual-energy CT imaging.

作者信息

Boninsegna Enrico, Piovan Enrico, Sozzi Carlo, Simonini Emilio, Aringhieri Giacomo, Cioni Dania, Neri Emanuele

机构信息

Department of Radiology and Neuroradiology, ASST Mantova, Mantua, Italy.

Academic Radiology, Department of Traslational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.

出版信息

Radiol Med. 2025 Feb;130(2):143-149. doi: 10.1007/s11547-024-01935-3. Epub 2024 Nov 21.

Abstract

OBJECTIVE

This study aimed to investigate the integration of dual-energy CT (DECT) into CT-guided bone biopsy procedures, comparing it with conventional CT techniques. The focus was on technical aspects, accuracy and radiation dose exposure.

MATERIALS AND METHODS

A total of 51 bone biopsies were conducted, with 36 using conventional CT and 15 utilizing DECT. Patient data, lesion characteristics and biopsy techniques were analyzed. Statistical analyses, including Fisher's exact test and independent samples t-test, were performed to compare accuracy and radiation doses between the two methods.

RESULTS

DECT-guided biopsies demonstrated a significantly higher accuracy (93.33%) compared to conventional CT biopsies (86.11%). The radiation dose exposure for DECT was comparable to conventional CT. DECT's ability to differentiate tissues, especially in bone marrow edema detection, led to higher precision.

CONCLUSION

Integrating DECT into CT-guided bone biopsies enhances tissue differentiation and accuracy without significantly increasing radiation exposure. This advancement holds promise for improving musculoskeletal interventional radiology, leading to more precise diagnoses, informed treatment decisions and improved patient outcomes.

摘要

目的

本研究旨在探讨双能CT(DECT)在CT引导下骨活检程序中的应用,并与传统CT技术进行比较。重点在于技术方面、准确性和辐射剂量暴露。

材料与方法

共进行了51例骨活检,其中36例使用传统CT,15例使用DECT。分析了患者数据、病变特征和活检技术。进行了包括Fisher精确检验和独立样本t检验在内的统计分析,以比较两种方法的准确性和辐射剂量。

结果

与传统CT活检(86.11%)相比,DECT引导下的活检显示出显著更高的准确性(93.33%)。DECT的辐射剂量暴露与传统CT相当。DECT区分组织的能力,尤其是在检测骨髓水肿方面,提高了活检的精度。

结论

将DECT整合到CT引导下的骨活检中可增强组织区分能力和准确性,且不会显著增加辐射暴露。这一进展有望改善肌肉骨骼介入放射学,实现更精确的诊断、明智的治疗决策并改善患者预后。

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