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提高CT引导下骨活检的精准度:探索双能CT成像的潜力。

Advancing precision in CT-guided bone biopsies: exploring the potential of dual-energy CT imaging.

作者信息

Boninsegna Enrico, Piovan Enrico, Sozzi Carlo, Simonini Emilio, Aringhieri Giacomo, Cioni Dania, Neri Emanuele

机构信息

Department of Radiology and Neuroradiology, ASST Mantova, Mantua, Italy.

Academic Radiology, Department of Traslational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.

出版信息

Radiol Med. 2025 Feb;130(2):143-149. doi: 10.1007/s11547-024-01935-3. Epub 2024 Nov 21.

DOI:10.1007/s11547-024-01935-3
PMID:39572472
Abstract

OBJECTIVE

This study aimed to investigate the integration of dual-energy CT (DECT) into CT-guided bone biopsy procedures, comparing it with conventional CT techniques. The focus was on technical aspects, accuracy and radiation dose exposure.

MATERIALS AND METHODS

A total of 51 bone biopsies were conducted, with 36 using conventional CT and 15 utilizing DECT. Patient data, lesion characteristics and biopsy techniques were analyzed. Statistical analyses, including Fisher's exact test and independent samples t-test, were performed to compare accuracy and radiation doses between the two methods.

RESULTS

DECT-guided biopsies demonstrated a significantly higher accuracy (93.33%) compared to conventional CT biopsies (86.11%). The radiation dose exposure for DECT was comparable to conventional CT. DECT's ability to differentiate tissues, especially in bone marrow edema detection, led to higher precision.

CONCLUSION

Integrating DECT into CT-guided bone biopsies enhances tissue differentiation and accuracy without significantly increasing radiation exposure. This advancement holds promise for improving musculoskeletal interventional radiology, leading to more precise diagnoses, informed treatment decisions and improved patient outcomes.

摘要

目的

本研究旨在探讨双能CT(DECT)在CT引导下骨活检程序中的应用,并与传统CT技术进行比较。重点在于技术方面、准确性和辐射剂量暴露。

材料与方法

共进行了51例骨活检,其中36例使用传统CT,15例使用DECT。分析了患者数据、病变特征和活检技术。进行了包括Fisher精确检验和独立样本t检验在内的统计分析,以比较两种方法的准确性和辐射剂量。

结果

与传统CT活检(86.11%)相比,DECT引导下的活检显示出显著更高的准确性(93.33%)。DECT的辐射剂量暴露与传统CT相当。DECT区分组织的能力,尤其是在检测骨髓水肿方面,提高了活检的精度。

结论

将DECT整合到CT引导下的骨活检中可增强组织区分能力和准确性,且不会显著增加辐射暴露。这一进展有望改善肌肉骨骼介入放射学,实现更精确的诊断、明智的治疗决策并改善患者预后。

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本文引用的文献

1
Dual Energy CT in Oncology: Benefits for Both Patients and Radiologists From an Emerging Quantitative and Functional Diagnostic Technique.双能 CT 在肿瘤学中的应用:一种新兴的定量和功能诊断技术对患者和放射科医生的双重获益。
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Quant Imaging Med Surg. 2023 Apr 1;13(4):2208-2217. doi: 10.21037/qims-22-372. Epub 2022 Aug 15.
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Image quality and dose exposure of contrast-enhanced abdominal CT on a 1st generation clinical dual-source photon-counting detector CT in obese patients vs. a 2nd generation dual-source dual energy integrating detector CT.
在肥胖患者中,第一代临床双源光子计数探测器 CT 与第二代双源双能积分探测器 CT 行腹部 CT 增强检查的图像质量和剂量暴露比较。
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Percutaneous bone biopsy.经皮骨活检。
Tech Vasc Interv Radiol. 2022 Mar;25(1):100800. doi: 10.1016/j.tvir.2022.100800. Epub 2022 Jan 16.
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Clinical indications for image-guided interventional procedures in the musculoskeletal system: a Delphi-based consensus paper from the European Society of Musculoskeletal Radiology (ESSR)-part VI, foot and ankle.骨骼肌肉系统影像引导介入操作的临床适应证:基于德尔菲法的欧洲骨骼肌肉放射学会(ESSR)共识文件——第六部分,足部和踝关节。
Eur Radiol. 2022 Feb;32(2):1384-1394. doi: 10.1007/s00330-021-08125-z. Epub 2021 Aug 25.
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CT-guided bone biopsy using electron density maps from dual-energy CT.使用双能CT电子密度图的CT引导下骨活检
Radiol Case Rep. 2021 Jul 1;16(9):2343-2346. doi: 10.1016/j.radcr.2021.06.009. eCollection 2021 Sep.
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Diagnostic accuracy of dual-energy CT for detecting bone marrow edema in patients with acute knee injuries: a systematic review and meta-analysis.双能 CT 诊断急性膝关节损伤患者骨髓水肿的准确性:系统评价和荟萃分析。
Skeletal Radiol. 2021 May;50(5):871-879. doi: 10.1007/s00256-020-03646-y. Epub 2020 Oct 22.
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CT-guided percutaneous biopsy of sclerotic bone lesions: diagnostic outcomes.CT引导下硬化性骨病变的经皮活检:诊断结果
Skeletal Radiol. 2018 May;47(5):661-669. doi: 10.1007/s00256-017-2828-x. Epub 2017 Dec 7.
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In vivo comparison of radiation exposure of dual-energy CT versus low-dose CT versus standard CT for imaging urinary calculi.双能CT、低剂量CT与标准CT在泌尿系统结石成像中的辐射暴露体内比较。
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