Wang Xiaoliang, Sun Zhenye, Ji Zhilin, Zhang Jingyu, Xiong Guangyi, Liu Jinwei, Wang Wei, Dong Shuhui, Meng Xianghong
Department of Radiology, Tianjin Hospital, No. 406, Jiefang South Road, Hexi District, Tianjin, China.
Department of Bone and Soft Tissue Oncology, Tianjin Hospital, No. 406, Jiefang South Road, Hexi District, Tianjin, China.
BMC Med Imaging. 2025 Apr 7;25(1):112. doi: 10.1186/s12880-025-01652-x.
Precision and operator expertise are critical for bone tumour biopsies. In this study, we investigated the impact of combining a soft guiding template with a laser device on the success rate of computed tomography (CT)-guided bone biopsies and the associated radiation dose.
A cohort of 114 patients with bone tumours requiring CT-guided biopsies were assigned to the auxiliary device group, utilising a soft guiding template and a laser device. Another 197 patients (control group) underwent biopsies with conventional guiding templates. The χ2 test compared biopsy success rates and concordance rates between biopsy findings and surgical outcomes. Biopsy success rates for limb bones, limb girdles, and axial bones were also compared. Independent sample t-tests analysed differences in age, volume CT dose index (CTDI), dose-length product (DLP), and effective dose (ED) between groups, as well as for limb bones, limb girdles, and axial bones individually.
The biopsy success rate in the auxiliary device group (85.09%) was significantly higher than in the control group (74.62%; P = 0.032). No significant differences were observed for limb girdles (P = 0.40) or axial bones (P = 0.19). However, the biopsy success rate for limb bones was significantly higher in the auxiliary device group (85.51%) than in the control group (70.87%; P = 0.028). The concordance rate between biopsy findings and surgical outcomes did not differ significantly (P = 1.00). CTDI showed no significant differences for limb girdles (P = 0.66), limb bones (P = 0.23), or axial bones (P = 0.8). While DLP (P = 0.41)and ED (P = 0.42) showed no significant differences for limb girdles, they were significantly lower for limb bones (DLP: P = 0.012; ED: P = 0.012) and axial bones (DLP: P = 0.005; ED: P = 0.002) in the auxiliary device group.
The combination of a soft guiding template and laser device significantly improved the success rate of CT-guided bone biopsies, providing a solid histological foundation for early and accurate diagnosis. Furthermore, these devices reduced the associated radiation dose, lowering radiation-related risks for patients.
精确性和操作者的专业技能对于骨肿瘤活检至关重要。在本研究中，我们调查了将软引导模板与激光设备相结合对计算机断层扫描（CT）引导下骨活检成功率及相关辐射剂量的影响。
将114例需要CT引导下活检的骨肿瘤患者纳入辅助设备组，使用软引导模板和激光设备。另外197例患者（对照组）采用传统引导模板进行活检。采用χ2检验比较活检成功率以及活检结果与手术结果之间的一致性率。还比较了四肢骨、四肢带骨和轴向骨的活检成功率。采用独立样本t检验分析两组之间以及四肢骨、四肢带骨和轴向骨各自在年龄、容积CT剂量指数（CTDI）、剂量长度乘积（DLP）和有效剂量（ED）方面的差异。
辅助设备组的活检成功率（85.09%）显著高于对照组（74.62%；P = 0.032）。四肢带骨（P = 0.40）和轴向骨（P = 用中文输出。19）未观察到显著差异。然而，辅助设备组四肢骨的活检成功率（85.51%）显著高于对照组（70.87%；P = 0.028）。活检结果与手术结果之间的一致性率无显著差异（P = 1.00）。CTDI在四肢带骨（P = 0.66）、四肢骨（P = 0.23）或轴向骨（P = 0.8）方面无显著差异。虽然DLP（P = 0.41）和ED（P = 0.42）在四肢带骨方面无显著差异，但在辅助设备组中，四肢骨（DLP：P = 0.012；ED：P = 0.012）和轴向骨（DLP：P = 0.005；ED：P = 0.002）的DLP和ED显著更低。
软引导模板和激光设备的组合显著提高了CT引导下骨活检的成功率，为早期准确诊断提供了坚实的组织学基础。此外，这些设备降低了相关辐射剂量，降低了患者的辐射相关风险。
