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软组织软骨瘤——15例肿瘤的研究

Soft tissue chondroma--a study of 15 tumours.

作者信息

Humphreys S, Pambakian H, McKee P H, Fletcher C D

出版信息

Histopathology. 1986 Feb;10(2):147-59. doi: 10.1111/j.1365-2559.1986.tb02470.x.

Abstract

Fifteen cases of soft tissue chondroma have been reviewed. This lesion shows an equal sex incidence and occurs predominantly in middle-aged individuals. The majority arise in the hands and feet. Histologically these tumours are largely composed of adult-type hyaline cartilage, but in all cases foci show nuclear atypia and pleomorphism. In cartilaginous lesions of the axial skeleton or large limb bones this would probably have led to a diagnosis of well differentiated chondrosarcoma. Despite these worrying features none of the seven cases for which follow-up information is available recurred. The importance of recognizing the benign nature of these little-known tumours is stressed. The differential diagnosis of soft tissue cartilaginous tumours is briefly discussed.

摘要

对15例软组织软骨瘤进行了回顾性研究。该病变在性别上发病率相等,主要发生于中年个体。大多数发生在手和足部。组织学上,这些肿瘤主要由成人型透明软骨组成,但在所有病例中均可见核异型性和多形性灶。在轴向骨骼或大肢体骨的软骨性病变中,这可能会导致诊断为高分化软骨肉瘤。尽管有这些令人担忧的特征,但有随访信息的7例病例均未复发。强调了认识这些鲜为人知肿瘤的良性性质的重要性。简要讨论了软组织软骨性肿瘤的鉴别诊断。

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