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阴道分娩产后出血的主要危险因素。

Risk Factors for Primary Postpartum Hemorrhage in Vaginal Delivery.

机构信息

Department of Obstetrics and Gynecology, Paropakar Maternity and Womens Hospital, Kathmandu.

Department of Obstetrics and Gynecology, Kathmandu Model Hospital, Kathmandu.

出版信息

J Nepal Health Res Counc. 2024 Oct 3;22(2):311-315. doi: 10.33314/jnhrc.v22i02.5384.

Abstract

BACKGROUND

Postpartum hemorrhage is an emergency, condition encountered in obstetric cases. It is an acute life-threatening situation and needs an immediate and rapid management. Postpartum hemorrhage is leading cause of maternal mortality and morbidity worldwide, with more commonly affecting women of developing countries. Accurate assessment of blood loss, identification of risk factors and timely recognition of postpartum hemorrhage remain major challenge in obstetrics. Different risk factors like hypertensive disorder in pregnancy, antepartum hemorrhage, anemia, big baby, polyhydramnios, multiple pregnancy, obesity, augmented/prolonged labor are risk factors for primary postpartum hemorrhage. The objective of this study was to identify the various risk factors associated with primary postpartum hemorrhage, in Paropakar Maternity and Women’s Hospital (PMWH), which is biggest institute in country for holding records of maximum number of deliveries.

METHODS

A cross sectional study was conducted over a period of 3 months between March 2023 to May 2023 on 72 patients. Women with term pregnancy who experienced primary PPH were analyzed for different risk factors. Similarly, incidence of postpartum hemorrhage according to age, parity, gestational age, types of labor, types of vaginal delivery and causes of postpartum hemorrhage were studied. The results were then analyzed.

RESULTS

The incidence of primary PPH during the study was 3%. Majority of cases of PPH were in age group of 20-24 (44.4%), followed by age group (25-29). Most of cases (50%) were of gravidity 2 to 3, followed by primigravida (45.8%). There was equal distribution of PPH in gestation age (37-39+6) WOG to (40-41+6) WOG. There were no risk factors associated with occurrence of PPH in 56%. Hypertensive disorder of pregnancy, anemia, APH, multiple pregnancy, fetal macrosomia, polyhydramnios and obesity are associated risk factors for PPH. Among risk factors associated with PPH, hypertensive disorder of pregnancy was most common risk factors (40.6%), followed by maternal anemia (25%), multiple pregnancy (12.5%), APH (6.3%) fetal macrosomia (6.3%), maternal obesity (6.3%), polyhydramnios (3.1%). PPH was more common in augmented labor (43%), followed by induced labor (29.2%) and spontaneous labor (27.8%). In this study most women ( 72.2%) experienced blood loss of 500-1000 ml. And most common cause of PPH was atony (83.3%) followed by genital tract injury (14%) and retained tissues (2.7%).

CONCLUSIONS

In many cases, PPH can’t be predicted fully as many cases of PPH occur without vivid risk factors, as in this study 56% women experiencing PPH had no associated antenatal risk factors. Antenatal risk factors like hypertensive disorder of pregnancy, maternal anemia, twin pregnancy, APH, macrosomia, obesity are common risk factors for PPH. Similarly induced and augmented labor and instrumental delivery can lead to PPH.

摘要

背景

产后出血是产科急症中常见的一种紧急情况。它是一种急性危及生命的情况,需要立即进行快速处理。产后出血是全球孕产妇死亡和发病的主要原因,发展中国家的妇女受其影响更为常见。准确评估出血量、识别风险因素以及及时识别产后出血仍然是产科的主要挑战。不同的风险因素,如妊娠期高血压疾病、产前出血、贫血、巨大儿、羊水过多、多胎妊娠、肥胖、催产/产程延长,都是原发性产后出血的风险因素。本研究的目的是确定与原发性产后出血相关的各种风险因素,该研究在 Paropakar 妇产医院(PMWH)进行,该医院是该国最大的拥有最多分娩记录的机构。

方法

本研究采用病例对照研究方法,于 2023 年 3 月至 2023 年 5 月期间对 72 名经历原发性 PPH 的患者进行了为期 3 个月的研究。对出现原发性 PPH 的孕妇进行不同风险因素的分析。同样,也研究了产后出血的发生率与年龄、产次、孕龄、分娩类型、阴道分娩类型和产后出血原因之间的关系。然后对结果进行分析。

结果

研究期间原发性 PPH 的发生率为 3%。大多数 PPH 病例发生在 20-24 岁年龄组(44.4%),其次是 25-29 岁年龄组。大多数病例(50%)为孕次 2-3 次,其次是初产妇(45.8%)。孕龄在 37-39+6 周和 40-41+6 周之间的 PPH 分布相等。56%的患者没有发生 PPH 的风险因素。妊娠期高血压疾病、贫血、APH、多胎妊娠、巨大儿、羊水过多和肥胖是 PPH 的相关风险因素。在与 PPH 相关的风险因素中,妊娠期高血压疾病是最常见的风险因素(40.6%),其次是产妇贫血(25%)、多胎妊娠(12.5%)、APH(6.3%)、巨大儿(6.3%)、产妇肥胖(6.3%)、羊水过多(3.1%)。PPH 在催产(43%)中更为常见,其次是引产(29.2%)和自然分娩(27.8%)。在这项研究中,大多数妇女(72.2%)的出血量为 500-1000ml。最常见的 PPH 原因是宫缩乏力(83.3%),其次是生殖道损伤(14%)和组织残留(2.7%)。

结论

在许多情况下,无法充分预测 PPH,因为许多 PPH 病例没有明显的风险因素,就像本研究中 56%的 PPH 患者没有相关的产前风险因素。产前风险因素,如妊娠期高血压疾病、产妇贫血、双胎妊娠、APH、巨大儿、肥胖是 PPH 的常见风险因素。同样,引产和催产以及器械分娩也会导致 PPH。

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