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特发性颅内高压合并高度近视患者中视盘周围神经纤维层萎缩伴发性视盘水肿的诊断挑战:病例报告。

Challenges in identifying papilledema amid myopic peripapillary atrophy in a patient with idiopathic intracranial hypertension and high myopia: a case report.

机构信息

Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.

出版信息

BMC Ophthalmol. 2024 Nov 21;24(1):506. doi: 10.1186/s12886-024-03772-4.

Abstract

BACKGROUND

Idiopathic intracranial hypertension (IIH) is a disease entity characterized by elevated intracranial pressure, which usually accompanied by papilledema. However, diagnosing papilledema can be challenging in patients with preexisting ocular conditions, such as high myopia.

CASE PRESENTATION

A 39-year-old woman with a long-standing history of high myopia presented with visual field constriction. Her visual acuity was decreased in both eyes, and she also reported morning headaches, pulsatile tinnitus, and intermittent periocular pain. Although she was diagnosed with IIH based on a cerebrospinal fluid study, there was no evident papilledema, which may have been masked by myopic changes in optic nerve and peripapillary retinal nerve fiber layer. After treatment for IIH with acetazolamide, her visual field and visual acuity markedly improved, and her symptoms were relieved.

CONCLUSIONS

In highly myopic patients, myopic changes in optic nerve head may obscure papilledema, complicating the diagnosis of IIH. This unusual case highlights the need for detailed history taking and a comprehensive clinical evaluation in patients with high myopia. Clinicians should suspect IIH in the presence of symptoms such as pulsatile tinnitus, morning headache, and visual field constriction, even in the absence of evident papilledema.

摘要

背景

特发性颅内高压(IIH)是一种以颅内压升高为特征的疾病实体,通常伴有视乳头水肿。然而,在存在先前眼部疾病的患者中,如高度近视,诊断视乳头水肿可能具有挑战性。

病例介绍

一名 39 岁女性,患有长期高度近视,出现视野缩小。她的双眼视力下降,还报告有晨发性头痛、搏动性耳鸣和间歇性眶周疼痛。尽管她根据脑脊液研究被诊断为 IIH,但没有明显的视乳头水肿,这可能被视神经和视盘周围视网膜神经纤维层的近视性改变所掩盖。在使用乙酰唑胺治疗 IIH 后,她的视野和视力明显改善,症状缓解。

结论

在高度近视患者中,视神经头的近视性改变可能会掩盖视乳头水肿,使 IIH 的诊断变得复杂。这个不寻常的病例强调了在高度近视患者中,详细的病史询问和全面的临床评估的必要性。临床医生应怀疑存在 IIH 的症状,如搏动性耳鸣、晨发性头痛和视野缩小,即使没有明显的视乳头水肿。

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