• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一项评价神经源性震颤母子干预模式作为青少年情绪障碍治疗辅助手段的有效性的随机对照试验研究方案。

Study protocol for a randomized controlled trial evaluating the effectiveness of a mother-child intervention model of neurogenic tremor as an add-on to treatment for emotional disorders in adolescents.

机构信息

Psychiatric Research Center, Beijing Huilongguan Hospital, Peking University Huilonguan Clinical Medical School, Beijing, IN, 100096, China.

State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, IN, 100875, China.

出版信息

BMC Complement Med Ther. 2024 Nov 21;24(1):403. doi: 10.1186/s12906-024-04650-8.

DOI:10.1186/s12906-024-04650-8
PMID:39574118
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11580556/
Abstract

BACKGROUND

Adolescents exhibit a high prevalence of mental health disorders, with more than half of all cases emerging before the age of 14 years. Since the advent of the COVID-19 pandemic, there has been a marked upsurge in anxiety and depression among adolescents across several nations. Emotional disorders often lead to severe outcomes, including school absenteeism, self-harm, and suicidal tendencies. The suboptimal efficacy of pharmacotherapy, compounded by limited availability and substantial costs associated with individual psychotherapy, underscores the critical need for identifying simple yet efficacious psychotherapeutic interventions suitable for both individual and group settings. Tension and Trauma Release Exercise (TRE) is a mind-body therapeutic approach that efficiently alleviates symptoms of anxiety and depression. This randomized controlled trial (RCT) aims to evaluate the effectiveness of a mother-child intervention model using TRE in enhancing the clinical management of adolescent patients diagnosed with emotional disorders.

METHODS

This study recruits 140 dyads of adolescents with emotional disorders and their mothers, randomly assigned to intervention or control groups. The intervention arm combines eight weeks of standard pharmacotherapy with an eight-week TRE group therapy, assessing at baseline, post-8-week treatment, and three-month follow-up. Initially, controls receive eight weeks of standard medication with parallel assessments, later transitioning to the same TRE intervention while maintaining continuous evaluation. The study further examines the influence of maternal emotional health on adolescent treatment response and investigates associated neurophysiological and psychological mechanisms.

DISCUSSION

This research endeavors to identify a straightforward and potent body-oriented psychological intervention that could improve the clinical outcomes for adolescent patients with emotional disorders. Such findings would carry profound implications not only for the healthy development of teenagers but also for potentially mitigating the burden on families, educational institutions, and society as a whole.

TRIAL REGISTRATION

ChiCTR2100044553, Registered March 24, 2021.

摘要

背景

青少年的心理健康障碍患病率较高,超过一半的病例发生在 14 岁之前。自 COVID-19 大流行以来,许多国家的青少年焦虑和抑郁情绪明显上升。情绪障碍常常导致严重后果,包括逃学、自残和自杀倾向。药物治疗效果不理想,再加上个别心理治疗的可用性有限和费用高昂,这突显了迫切需要确定适合个体和团体环境的简单而有效的心理治疗干预措施。张力与紧张释放练习(TRE)是一种身心治疗方法,可有效缓解焦虑和抑郁症状。这项随机对照试验(RCT)旨在评估使用 TRE 的母子干预模式对增强情绪障碍青少年患者临床管理的有效性。

方法

本研究招募了 140 对患有情绪障碍的青少年及其母亲,随机分为干预组和对照组。干预组结合了 8 周的标准药物治疗和 8 周的 TRE 团体治疗,在基线、8 周治疗后和 3 个月随访时进行评估。最初,对照组接受 8 周的标准药物治疗和平行评估,然后过渡到相同的 TRE 干预,同时保持持续评估。该研究还研究了母亲情绪健康对青少年治疗反应的影响,并调查了相关的神经生理和心理机制。

讨论

本研究旨在确定一种简单而有效的身体导向的心理干预措施,可以改善情绪障碍青少年患者的临床结果。这些发现不仅对青少年的健康发展具有深远意义,而且有可能减轻家庭、教育机构和整个社会的负担。

试验注册

ChiCTR2100044553,于 2021 年 3 月 24 日注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28ef/11580556/ea737fcb3fd5/12906_2024_4650_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28ef/11580556/ea737fcb3fd5/12906_2024_4650_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28ef/11580556/ea737fcb3fd5/12906_2024_4650_Fig1_HTML.jpg

相似文献

1
Study protocol for a randomized controlled trial evaluating the effectiveness of a mother-child intervention model of neurogenic tremor as an add-on to treatment for emotional disorders in adolescents.一项评价神经源性震颤母子干预模式作为青少年情绪障碍治疗辅助手段的有效性的随机对照试验研究方案。
BMC Complement Med Ther. 2024 Nov 21;24(1):403. doi: 10.1186/s12906-024-04650-8.
2
Clinical and cost-effectiveness of parenting intervention for mothers experiencing psychosocial stress: insights from the early closure of the Mellow Babies RCT.针对经历心理社会压力的母亲的育儿干预措施的临床效果及成本效益:来自“温柔宝贝”随机对照试验提前结束的启示
Public Health Res (Southampt). 2024 Dec;12(17):1-115. doi: 10.3310/KCVL7125.
3
Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.在流行地区,服用抗叶酸抗疟药物的人群中,叶酸补充剂与疟疾易感性和严重程度的关系。
Cochrane Database Syst Rev. 2022 Feb 1;2(2022):CD014217. doi: 10.1002/14651858.CD014217.
4
Building Emotional Awareness and Mental Health (BEAM): study protocol for a phase III randomized controlled trial of the BEAM app-based program for mothers of children 18-36 months.建立情绪意识和心理健康(BEAM):基于应用程序的 BEAM 项目对 18-36 个月儿童的母亲进行的 III 期随机对照试验的研究方案。
Trials. 2022 Sep 5;23(1):741. doi: 10.1186/s13063-022-06512-5.
5
Efficacy of Parent-Infant-Psychotherapy with mothers with postpartum mental disorder: study protocol of the randomized controlled trial as part of the SKKIPPI project.母婴心理治疗对产后精神障碍母亲的疗效:作为 SKKIPPI 项目一部分的随机对照试验研究方案。
Trials. 2020 Jun 5;21(1):490. doi: 10.1186/s13063-020-04443-7.
6
Efficacy of parent-infant psychotherapy compared to care as usual in children with regulatory disorders in clinical and outpatient settings: study protocol of a randomised controlled trial as part of the SKKIPPI project.在临床和门诊环境中,针对有调节障碍的儿童,与常规护理相比,父母-婴儿心理疗法的疗效:作为 SKKIPPI 项目一部分的一项随机对照试验的研究方案。
BMC Psychiatry. 2021 Feb 27;21(1):118. doi: 10.1186/s12888-021-03112-6.
7
Interpersonal counselling for adolescent depression delivered by youth mental health workers without core professional training: the ICALM feasibility RCT.由未经核心专业培训的青年心理健康工作者提供的青少年抑郁症人际咨询:ICALM可行性随机对照试验
Health Soc Care Deliv Res. 2024 Dec;12(48):1-121. doi: 10.3310/GTRV6410.
8
Early intervention to prevent adverse child emotional and behavioural development following maternal depression in pregnancy: study protocol for a randomised controlled trial.孕期抑郁后预防儿童情绪和行为发育不良的早期干预:一项随机对照试验的研究方案。
BMC Psychol. 2023 Aug 4;11(1):222. doi: 10.1186/s40359-023-01244-w.
9
Behavioural modification interventions for medically unexplained symptoms in primary care: systematic reviews and economic evaluation.行为修正干预对初级保健中无法用医学解释的症状:系统评价和经济评估。
Health Technol Assess. 2020 Sep;24(46):1-490. doi: 10.3310/hta24460.
10
The effectiveness of the peer delivered Thinking Healthy Plus (THPP+) Programme for maternal depression and child socio-emotional development in Pakistan: study protocol for a three-year cluster randomized controlled trial.同伴提供的“健康思维升级版”(THPP+)项目对巴基斯坦孕产妇抑郁症和儿童社会情感发展的有效性:一项为期三年的整群随机对照试验的研究方案
Trials. 2016 Sep 8;17(1):442. doi: 10.1186/s13063-016-1530-y.

本文引用的文献

1
Changes in Depression and Anxiety Among Children and Adolescents From Before to During the COVID-19 Pandemic: A Systematic Review and Meta-analysis.儿童和青少年在 COVID-19 大流行前后的抑郁和焦虑变化:系统评价和荟萃分析。
JAMA Pediatr. 2023 Jun 1;177(6):567-581. doi: 10.1001/jamapediatrics.2023.0846.
2
Controversies in the Pharmacotherapy of Adolescent Depression.青少年抑郁症药物治疗的争议。
Curr Pharm Des. 2022;28(24):1975-1984. doi: 10.2174/1381612828666220526150153.
3
Internet-Delivered Interventions for Depression and Anxiety Symptoms in Children and Young People: Systematic Review and Meta-analysis.
互联网干预对儿童和青少年抑郁与焦虑症状的影响:系统评价与荟萃分析
JMIR Pediatr Parent. 2022 May 12;5(2):e33551. doi: 10.2196/33551.
4
Psychometric Properties of the Chinese Version of the Functional Assessment of Self-Mutilation (FASM) in Chinese Clinical Adolescents.中文版自我伤害功能评估量表(FASM)在中国临床青少年群体中的心理测量学特性
Front Psychiatry. 2022 Jan 26;12:755857. doi: 10.3389/fpsyt.2021.755857. eCollection 2021.
5
Fear balance is maintained by bodily feedback to the insular cortex in mice.恐惧平衡是通过躯体反馈到小鼠的脑岛皮层来维持的。
Science. 2021 Nov 19;374(6570):1010-1015. doi: 10.1126/science.abj8817. Epub 2021 Nov 18.
6
How to assess and interpret everyday life salivary cortisol measures: A tutorial on practical and statistical considerations.如何评估和解读日常生活中的唾液皮质醇水平:关于实用和统计考虑因素的教程。
Psychoneuroendocrinology. 2021 Nov;133:105391. doi: 10.1016/j.psyneuen.2021.105391. Epub 2021 Aug 14.
7
Tension and trauma releasing exercises for people with multiple sclerosis - An exploratory pilot study.针对多发性硬化症患者的张力与创伤释放练习——一项探索性初步研究。
J Tradit Complement Med. 2021 Feb 8;11(5):383-389. doi: 10.1016/j.jtcme.2021.02.003. eCollection 2021 Sep.
8
Global Prevalence of Depressive and Anxiety Symptoms in Children and Adolescents During COVID-19: A Meta-analysis.新冠疫情期间儿童和青少年抑郁和焦虑症状的全球患病率:一项荟萃分析。
JAMA Pediatr. 2021 Nov 1;175(11):1142-1150. doi: 10.1001/jamapediatrics.2021.2482.
9
A systematic review of suicide and suicide attempts in adolescents with psychotic disorders.精神病性障碍青少年自杀和自杀未遂的系统评价
Schizophr Res. 2021 Sep;235:80-90. doi: 10.1016/j.schres.2021.07.029. Epub 2021 Jul 28.
10
The effect of a mindfulness-based stress intervention on neurobiological and symptom measures in adolescents with early life stress: a randomized feasibility study.基于正念的压力干预对有早期生活压力的青少年神经生物学和症状测量的影响:一项随机可行性研究。
BMC Complement Med Ther. 2021 Apr 15;21(1):123. doi: 10.1186/s12906-021-03295-1.