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病例报告:通过计算流体动力学分析A型主动脉夹层修复术后狭窄真腔内壁面剪应力的增加

Case Report: Increase in wall shear stress in a narrowed true lumen after type A aortic dissection repair analyzed by computed fluid dynamics.

作者信息

Iida Yasunori, Marushita Yoichi, Motohashi Yuka, Sato Toshio

机构信息

Department of Cardiovascular Surgery, Saiseikai Yokohamashi Tobu Hospital, Yokohama, Japan.

Department of Clinical Engineering, Faculty of Medical Science and Technology, Gunma Paz University, Takasaki, Japan.

出版信息

Front Cardiovasc Med. 2024 Nov 7;11:1478430. doi: 10.3389/fcvm.2024.1478430. eCollection 2024.

DOI:10.3389/fcvm.2024.1478430
PMID:39574777
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11578975/
Abstract

A 46-year-old man suffered from acute type A aortic dissection (TAAD) and underwent total arch replacement using the frozen elephant trunk (FET) procedure. During follow-up, we noted back pain and found distal stent graft-induced new entry (dSINE) at the FET distal part by computed tomography. We performed additional extended thoracic endovascular aortic repair (TEVAR) for this pathology. The time between TAAD repair and TEVAR was 2 months. We investigated this complication by computational fluid dynamics analysis through pre- and post-dSINE. The results showed increased wall shear stress at the narrowed true lumen (TL) site, not at the FET site, indicating that prestenotic hydrodynamic load may affect dSINE occurrence.

摘要

一名46岁男性患有急性A型主动脉夹层(TAAD),并接受了使用冰冻象鼻技术(FET)的全弓置换术。在随访期间,我们注意到患者出现背痛,并通过计算机断层扫描在FET远端发现了远端支架移植物引起的新破口(dSINE)。我们针对这一病变进行了额外的胸段主动脉腔内修复术(TEVAR)。TAAD修复与TEVAR之间的时间间隔为2个月。我们通过dSINE前后的计算流体动力学分析对这一并发症进行了研究。结果显示,狭窄真腔(TL)部位而非FET部位的壁面剪应力增加,这表明狭窄前的流体动力负荷可能影响dSINE的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e82/11578975/eb34a1f18490/fcvm-11-1478430-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e82/11578975/fbfd06e87311/fcvm-11-1478430-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e82/11578975/eb34a1f18490/fcvm-11-1478430-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e82/11578975/fbfd06e87311/fcvm-11-1478430-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e82/11578975/eb34a1f18490/fcvm-11-1478430-g002.jpg

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Case Report: Increase in wall shear stress in a narrowed true lumen after type A aortic dissection repair analyzed by computed fluid dynamics.病例报告:通过计算流体动力学分析A型主动脉夹层修复术后狭窄真腔内壁面剪应力的增加
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本文引用的文献

1
Utility of computational fluid dynamics for prediction of efficacy of the surgical interventions for aortic coarctation in adults.计算流体动力学在预测成人主动脉缩窄手术干预疗效中的应用。
JTCVS Tech. 2023 Jan 13;18:16-21. doi: 10.1016/j.xjtc.2023.01.007. eCollection 2023 Apr.
2
First insights into the role of wall shear stress in the development of a distal stent graft induced new entry through computational fluid dynamics simulations.通过计算流体动力学模拟首次深入了解壁面剪应力在远端支架移植物诱导新入口形成中的作用。
J Thorac Dis. 2023 Feb 28;15(2):281-290. doi: 10.21037/jtd-22-1206. Epub 2023 Feb 13.
3
(s)INE: (soft-graft)-induced new entry tear after elephant trunk procedure.
(s)INE:象鼻手术后(软移植)诱导的新的入口性撕裂。
Interdiscip Cardiovasc Thorac Surg. 2023 Jan 9;36(1). doi: 10.1093/icvts/ivac283.
4
Distal Stent Graft-Induced New Entry After TEVAR or FET: Insights Into a New Disease From EuREC.覆膜支架远端新入口形成:EUREC 研究带来的一种新疾病的洞见
Ann Thorac Surg. 2020 Nov;110(5):1494-1500. doi: 10.1016/j.athoracsur.2020.02.079. Epub 2020 Apr 10.
5
Distal Stent Graft-Induced New Entries After the Frozen Elephant Trunk Procedure.冰冻象鼻技术后,支架型人工血管远端新入口。
Ann Thorac Surg. 2020 Oct;110(4):1271-1279. doi: 10.1016/j.athoracsur.2020.02.017. Epub 2020 Mar 16.