Fagan Patrick, McLaughlin Conor J, Fugok Kimberly L, Desai Tasha
Department of Emergency and Hospital Medicine, Lehigh Valley Health Network/University of South Florida (USF) Morsani College of Medicine, Bethlehem, USA.
Department of Emergency and Hospital Medicine, Division of Pediatric Emergency Medicine, Lehigh Valley Health Network/University of South Florida (USF) Morsani College of Medicine, Bethlehem, USA.
Cureus. 2024 Oct 22;16(10):e72138. doi: 10.7759/cureus.72138. eCollection 2024 Oct.
Pheochromocytomas are rare tumors arising from the chromaffin cells of the adrenal medulla that result in the secretion of excessive catecholamines. They are an uncommon cause of hypertension in the pediatric population. We present a case of a six-year-old male with hypertension, rapid weight loss, palpitations, excessive sweating, and vomiting. Their previous medical history was significant for congenital hypothyroidism, and upon the emergence of his symptoms, his levothyroxine dosing was reduced to half. Presenting symptoms and initial history were suspicious for thyroid-related disease; however, imaging showed a complex right adrenal mass in the setting of elevated plasma catecholamine levels. A diagnosis of pheochromocytoma was made, and a right adrenalectomy was performed. The patient tolerated the procedure well, with complete resolution of symptoms. Three years later, his symptoms re-emerged and were concerning for tumor recurrence. This case highlights the diagnosis of this rare cause of pediatric hypertension and the importance of remaining vigilant against anchoring bias.
嗜铬细胞瘤是起源于肾上腺髓质嗜铬细胞的罕见肿瘤,可导致过量儿茶酚胺分泌。它们是儿童高血压的罕见病因。我们报告一例6岁男性患者,有高血压、体重快速减轻、心悸、多汗和呕吐症状。其既往病史有先天性甲状腺功能减退,出现症状后,左甲状腺素剂量减至一半。出现的症状和初始病史怀疑为甲状腺相关疾病;然而,影像学检查显示在血浆儿茶酚胺水平升高的情况下右侧肾上腺有一复杂肿块。诊断为嗜铬细胞瘤,并进行了右侧肾上腺切除术。患者对手术耐受良好,症状完全缓解。三年后,他的症状再次出现,担心肿瘤复发。该病例突出了这种儿童高血压罕见病因的诊断以及警惕锚定偏差的重要性。