Jeong Yeonsu, Rha Min-Seok, Kim Chang-Hoon, Cho Hyung-Ju
Department of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University College of Medicine, Seoul, Korea.
Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Head Neck. 2025 Apr;47(4):1071-1078. doi: 10.1002/hed.28007. Epub 2024 Nov 22.
This first prospective study evaluates the efficacy and safety of single-port transoral robotic surgery (SP TORS) for tongue base resection (TBR) in obstructive sleep apnea (OSA) patients.
A single-center, single-surgeon clinical investigation enrolled 25 subjects from April 2021 to September 2022. Pre- and postsurgery polysomnography reports and standardized sleep quality assessments were collected. Surgical parameters and complications were documented.
According to Sher's success criteria (50% reduction in AHI and AHI < 20), the success rate was 76% (19/25 patients). Preoperative AHI decreased from 58.56 ± 26.40 to 18.19 ± 22.02 postsurgery. Symptoms such as foreign body sensation and taste dysfunction improved within 3 months. Major complications, including hemorrhage, occurred in two patients (8%).
SP TORS TBR effectively manages OSA, significantly improving AHI outcomes and safety. Its precision and targeted tissue removal highlight its advantages over traditional methods, warranting further clinical investigation. Traial Registration: ClinicalTrials.gov identifier: NCT04795817.
这项首个前瞻性研究评估了单孔经口机器人手术（SP TORS）用于阻塞性睡眠呼吸暂停（OSA）患者舌根切除术（TBR）的疗效和安全性。
一项单中心、由单一外科医生进行的临床研究于2021年4月至2022年9月招募了25名受试者。收集术前和术后多导睡眠图报告以及标准化睡眠质量评估。记录手术参数和并发症。
根据谢尔的成功标准（呼吸暂停低通气指数[AHI]降低50%且AHI＜20），成功率为76%（19/25例患者）。术前AHI从58.56±26.40降至术后的18.19±22.02。异物感和味觉功能障碍等症状在3个月内有所改善。包括出血在内的主要并发症发生在两名患者中（8%）。
SP TORS TBR能有效治疗OSA，显著改善AHI结果和安全性。其精确性和靶向组织切除突出了其相对于传统方法的优势，值得进一步临床研究。试验注册：ClinicalTrials.gov标识符：NCT04795817。
