Reshma C S, Remya S, Bindu J
Faculty of Ocean Science and Technology, Kerala University of Fisheries and Ocean Studies Panangad, Kerala, 682506, India; Fish Processing Division, ICAR - Central Institute of Fisheries Technology (CIFT), Cochin, Kerala, 682029, India.
Fish Processing Division, ICAR - Central Institute of Fisheries Technology (CIFT), Cochin, Kerala, 682029, India.
Int J Biol Macromol. 2024 Dec;283(Pt 4):137905. doi: 10.1016/j.ijbiomac.2024.137905. Epub 2024 Nov 20.
Polylactic acid (PLA) is an aliphatic polyester, which is primarily synthesized from renewable resources through the polycondensation or ring-opening polymerization of lactic acid (LA)/lactide. LA can be conveniently produced via the fermentation of sugars obtained from renewable sources such as corn and sugar cane. Due to its biodegradable and biocompatible nature, PLA exhibits a vast range of applications. Its advantages include non-toxicity, environmental safety, and compatibility with human biological systems. PLA finds significant use in various biomedical applications, including implants, tissue engineering, sutures, and drug delivery systems. Additionally, PLA serves as a renewable and biodegradable polymer of extensive utility in film production, offering an alternative to petrochemical-based polymers. Moreover, the properties of PLA-based films can be tailored by incorporating extracts, polysaccharides, proteins, and nano-particles. This review encompasses LA production, PLA synthesis, and diverse applications of PLA and further explores the potential of PLA in the realm of packaging.
聚乳酸(PLA)是一种脂肪族聚酯,主要通过乳酸(LA)/丙交酯的缩聚或开环聚合由可再生资源合成。LA可以通过发酵从玉米和甘蔗等可再生来源获得的糖方便地生产。由于其可生物降解和生物相容的性质,PLA具有广泛的应用。其优点包括无毒、环境安全以及与人体生物系统的相容性。PLA在各种生物医学应用中有着重要用途,包括植入物、组织工程、缝合线和药物递送系统。此外,PLA作为一种可再生且可生物降解的聚合物,在薄膜生产中具有广泛用途,为基于石化的聚合物提供了一种替代品。而且,基于PLA的薄膜的性能可以通过加入提取物、多糖、蛋白质和纳米颗粒来进行调整。这篇综述涵盖了LA的生产、PLA的合成以及PLA的各种应用,并进一步探讨了PLA在包装领域的潜力。