Park Hong Kyu, Shim Young Suk
Department of Pediatrics, Gyeongsang National University College of Medicine, Jinju, Korea.
Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea.
Hypertens Res. 2025 Mar;48(3):1003-1011. doi: 10.1038/s41440-024-02000-2. Epub 2024 Nov 22.
The prevalence of hypertension among children and adolescents has risen to 4% globally in recent decades, presenting a significant public health challenge due to its association with increased cardiovascular risks. Existing research on the transmission of hypertension risk between parents and offspring lacks comprehensive data from general population-based samples with clinically collected measurements spanning generations. This study utilized nationally representative data to assess the risk of developing hypertension in offspring based on parental hypertension status, employing standardized blood pressure measurements rather than relying solely on historical data. A positive correlation exists between the increasing number of hypertensive parents and the risk of hypertension development in offspring. The prevalence of hypertension among individuals aged 10 to 18 years did not substantially increase with age. Adolescents whose parents were affected by hypertension exhibited a 2-fold greater prevalence of hypertension compared to the general population with the same age, with approximately a quarter of boys with both hypertensive parents having hypertension. Among nonobese individuals, the risk of hypertension associated with parental hypertension was comparable to that observed in obese subjects. Blood pressure monitoring from the early stage of life would benefit adolescents with hypertensive parents.
近几十年来,全球儿童和青少年高血压患病率已升至4%,由于其与心血管风险增加相关,这带来了重大的公共卫生挑战。现有的关于父母与子女之间高血压风险传递的研究缺乏来自基于普通人群样本的全面数据,这些样本没有经过几代人的临床测量。本研究利用具有全国代表性的数据,基于父母的高血压状况评估后代患高血压的风险,采用标准化血压测量而非仅依赖历史数据。高血压父母数量的增加与后代患高血压的风险之间存在正相关。10至18岁个体的高血压患病率并未随年龄大幅增加。父母患有高血压的青少年患高血压的患病率比同龄普通人群高2倍,父母双方均患有高血压的男孩中约有四分之一患有高血压。在非肥胖个体中,与父母高血压相关的高血压风险与肥胖个体中观察到的风险相当。从生命早期开始进行血压监测将使父母患有高血压的青少年受益。