Institute of Public Health and Clinical Nutrition, General Practice, University of Eastern Finland, P. O BOX 1627, Kuopio, FI-70211, Finland.
Rantakylä Health Centre, Wellbeing services of North Karelia, Joensuu, Finland.
BMC Prim Care. 2024 Nov 22;25(1):398. doi: 10.1186/s12875-024-02651-7.
The aim of this study was to evaluate the association between living alone and mortality among older patients with and without diabetes.
Electronic patient records were used to identify patients at least 65 years of age with a diagnosis of diabetes and two age- and sex-matched controls without diabetes for each patient with diabetes in 2015. The study population in this analysis consisted of 429 patients with diabetes and 650 controls who returned a questionnaire that contained questions about their diseases, symptoms, and functions. The mortality (2015-2019) data were based on the national registry of Statistics Finland. Cumulative mortality was estimated with Kaplan-Meier's method and compared with the log-rank test. Cox proportional hazards regression was used to estimate the adjusted hazard ratios (HR) and their 95% confidence intervals (CI).
The median follow-up time was 4.3 years. 208 of the controls (32%) and 156 (36%) of the patients with diabetes lived alone. Of the controls, 8.1% (95% CI 5.9-11.1) of those not living alone and 20.2% (95% CI 15.3-26.3) living alone died. The corresponding numbers for patients with diabetes were 15.1% (95% CI 11.3-19.8) and 28.8% (95% CI 22.4-36.7). Among all patients, living alone was associated with increased mortality (HR = 1.84; 95% Cl 1.30-2.61), whereas the diagnosis of diabetes was not (HR = 1.31; 95% Cl 0.94-1.81).
The results of this study show that living alone had a significant impact on the mortality of older patients, regardless of whether they had diabetes or not. Diabetes was not clearly associated with the increased mortality among these older home-dwelling patients.
本研究旨在评估独居与有或无糖尿病的老年患者死亡率之间的关系。
利用电子病历,于 2015 年为每例糖尿病患者匹配至少 65 岁、患有糖尿病且性别和年龄相匹配的对照者各 1 名,以此识别出患者。本分析的研究人群包括 429 例糖尿病患者和 650 例回答了有关其疾病、症状和功能的问卷的对照者。死亡率(2015-2019 年)数据基于芬兰国家统计局的登记数据。采用 Kaplan-Meier 法估计累积死亡率,并与对数秩检验进行比较。Cox 比例风险回归用于估计调整后的风险比(HR)及其 95%置信区间(CI)。
中位随访时间为 4.3 年。对照组中 208 例(32%)和糖尿病组中 156 例(36%)独居。对照组中,非独居者的死亡率为 8.1%(95%CI 5.9-11.1),独居者的死亡率为 20.2%(95%CI 15.3-26.3)。糖尿病患者的相应数字分别为 15.1%(95%CI 11.3-19.8)和 28.8%(95%CI 22.4-36.7)。在所有患者中,独居与死亡率增加相关(HR=1.84;95%CI 1.30-2.61),而糖尿病诊断则无此相关性(HR=1.31;95%CI 0.94-1.81)。
本研究结果表明,独居对无论是否患有糖尿病的老年患者的死亡率都有显著影响。对于这些居住在自己家中的老年患者,糖尿病与死亡率增加并无明显关联。