Department of Plastic Surgery, Copenhagen University Hospital, Herlev and Gentofte, Herlev, Denmark.
Department of Oncology, Cancer Survivorship and Late Effects Research Center (CASTLE), Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Acta Oncol. 2024 Nov 24;63:909-914. doi: 10.2340/1651-226X.2024.41037.
We developed the Melacare nurse-led intervention, which combines education in skin self-examination as a resource-conscious approach to detecting recurrence and management of fear of cancer recurrence in patients treated for melanoma. This publication presents the Melacare study protocol and evaluates the feasibility and acceptability of Melacare prior to a larger randomised controlled trial.
Feasibility and acceptability of Melacare were evaluated in an intervention-only feasibility study, in which patients attended two nurse-led intervention sessions coupled with an educational booklet. Participants completed patient-reported outcome (PRO) questionnaires at baseline and before each session. After the intervention, participants completed a study-specific feedback questionnaire. Feasibility was evaluated in terms of recruitment, adherence, and attendance. Self-reported outcomes from the study-specific questionnaire on intervention effects were also collected. Results of the feasibility study: Fourteen patients (nine stage IA, five stage IB melanoma) participated. Attendance and recruitment rates were 100%, all participants completed the baseline and PRO questionnaires, and 100% read at least half of the educational booklet. In terms of intervention effects, all patients reported improved knowledge of performing skin self-examination and coping with the fear of cancer recurrence.
Results indicate that the Melacare nurse-led intervention is highly feasible and acceptable for use with patients treated for early-stage melanoma. Prior to clinical trial commencement, minor refinements include changing the method of recruiting by telephone and offering.
我们开发了 Melacare 护士主导的干预措施，它将皮肤自我检查的教育与资源意识相结合，以检测黑色素瘤治疗后患者的复发情况并管理其对癌症复发的恐惧。本出版物介绍了 Melacare 研究方案，并在更大规模的随机对照试验之前评估了 Melacare 的可行性和可接受性。
在一项仅干预的可行性研究中评估了 Melacare 的可行性和可接受性，该研究中患者参加了两次护士主导的干预课程，并附有教育手册。参与者在基线和每次课程前完成了患者报告的结局（PRO）问卷。干预后，参与者完成了一项专门针对研究的反馈问卷。根据招募、依从性和出勤率来评估可行性。还收集了研究专用问卷中关于干预效果的自我报告结果。可行性研究的结果：共有 14 名患者（9 名 I 期 A 黑色素瘤，5 名 I 期 B 黑色素瘤）参与。出勤率和招募率为 100%，所有参与者均完成了基线和 PRO 问卷，并且 100%的人至少阅读了教育手册的一半。就干预效果而言，所有患者均报告称，他们对进行皮肤自我检查和应对癌症复发恐惧的知识有所提高。
结果表明，Melacare 护士主导的干预措施对于接受早期黑色素瘤治疗的患者非常可行且可接受。在开始临床试验之前，需要进行一些微小的改进，包括通过电话招募患者并提供。
