Rezagholizade-Shirvan Alieh, Soltani Mahya, Shokri Samira, Radfar Ramin, Arab Masoumeh, Shamloo Ehsan
Department of Food Science and Technology, Neyshabur University of Medical Sciences, Neyshabur, Iran.
Student Research Committee, Department of Food Science and Technology, School of Nutrition Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Food Chem X. 2024 Nov 2;24:101953. doi: 10.1016/j.fochx.2024.101953. eCollection 2024 Dec 30.
Nanotechnology plays a pivotal role in food science, particularly in the nanoencapsulation of bioactive compounds, to enhance their stability, bioavailability, and therapeutic potential. This review aims to provide a comprehensive analysis of the encapsulation of bioactive compounds, emphasizing the characteristics, food applications, and implications for human health. This work offers a detailed comparison of polymers such as sodium alginate, gum Arabic, chitosan, cellulose, pectin, shellac, and xanthan gum, while also examining both conventional and emerging encapsulation techniques, including freeze-drying, spray-drying, extrusion, coacervation, and supercritical anti-solvent drying. The contribution of this review lies in highlighting the role of encapsulation in improving system stability, controlling release rates, maintaining bioactivity under extreme conditions, and reducing lipid oxidation. Furthermore, it explores recent technological advances aimed at optimizing encapsulation processes for targeted therapies and functional foods. The findings underline the significant potential of encapsulation not only in food supplements and functional foods but also in supportive medical treatments, showcasing its relevance to improving human health in various contexts.
纳米技术在食品科学中起着关键作用，特别是在生物活性化合物的纳米包封方面，以提高其稳定性、生物利用度和治疗潜力。本综述旨在对生物活性化合物的包封进行全面分析，重点关注其特性、食品应用以及对人类健康的影响。这项工作对海藻酸钠、阿拉伯胶、壳聚糖、纤维素、果胶、虫胶和黄原胶等聚合物进行了详细比较，同时还研究了传统和新兴的包封技术，包括冷冻干燥、喷雾干燥、挤压、凝聚和超临界抗溶剂干燥。本综述的贡献在于强调包封在提高体系稳定性、控制释放速率、在极端条件下保持生物活性以及减少脂质氧化方面的作用。此外，它还探讨了旨在优化靶向治疗和功能性食品包封工艺的最新技术进展。研究结果强调了包封不仅在食品补充剂和功能性食品中，而且在辅助医疗治疗中具有巨大潜力，展示了其在各种情况下对改善人类健康的相关性。
