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良性前列腺增生患者经尿道前列腺切除术后并发症的回顾性评估:急性尿潴留的影响

Retrospective Assessment of Post-Transurethral Resection of the Prostate Complications in Benign Prostatic Hyperplasia Patients: Impact of Acute Urinary Retention.

作者信息

Ahmed Mohammed M, Prasannakumary Rithi, Ravichandran Abhinaya, Nazir Azlan N, Gnanavelu Hariprasad, Pascal Shoraf, Mittal Gaurav

机构信息

Urology, Queen Alexandra Hospital, Portsmouth, GBR.

Surgery, Shyam Shah Medical College, Rewa, IND.

出版信息

Cureus. 2024 Oct 23;16(10):e72223. doi: 10.7759/cureus.72223. eCollection 2024 Oct.

Abstract

Background Benign prostatic hyperplasia (BPH) is the most common urological condition affecting older men, leading to lower urinary tract symptoms (LUTS) and complications such as acute urinary retention (AUR), which can significantly impact quality of life. This study aims at comparing the postoperative outcomes and complication rates of monopolar transurethral resection of the prostate (TURP) in BPH patients with and without AUR. By examining the differences in postoperative outcomes, the study seeks to highlight the impact of AUR on complications such as UTIs, prolonged catheterization, and extended hospital stays, and assess the potential clinical implications for improving treatment strategies in these patients. Methodology  An observational retrospective study was conducted at a tertiary care hospital in central India, over a period of two years. The study included 150 men aged 45 to 70 years with LUTS due to BPH, and participants were equally divided between two groups: Group A (AUR positive) and Group B (AUR negative). Wide-ranging assessments were performed on all patients, including history, physical examination, digital rectal examination, ultrasound, and post-void residual (PVR) urine assessment. Postoperative outcomes and complications were determined, and statistical analyses were conducted using Student's t-test with a level of significance of p < 0.05. Results The findings of the study indicated that patients in Group A, who experienced AUR, had significantly higher postoperative complications compared to Group B, who did not have AUR. Specifically, the mean complication rate was 60% in Group A compared to 30% in Group B. Common complications included urinary tract infections and prolonged hospital stays. In terms of urodynamic parameters, Group A exhibited a significantly lower maximum flow rate (Qmax) at 7.5 mL/s compared to 9.8 mL/s in Group B (p < 0.01). The average PVR volume was also notably higher in Group A at 150.4 mL, compared to 90.2 mL in Group B (p < 0.01). These differences highlight the impact of AUR on surgical outcomes. Conclusion  The findings of this study highlight the increased risks of complications associated with AUR in patients undergoing monopolar TURP. These results underscore the need for careful patient selection and management strategies to optimize outcomes. Future research should focus on expanding the sample size and incorporating multicenter data to enhance the generalizability of the results. Additionally, further investigation into long-term outcomes and the effectiveness of different management protocols for patients with AUR will be essential for improving the quality of care in the management of BPH.

摘要

背景

良性前列腺增生(BPH)是影响老年男性的最常见泌尿系统疾病,可导致下尿路症状(LUTS)以及诸如急性尿潴留(AUR)等并发症,这会对生活质量产生重大影响。本研究旨在比较患有和未患有AUR的BPH患者经尿道前列腺单极切除术(TURP)的术后结果和并发症发生率。通过检查术后结果的差异,该研究旨在突出AUR对诸如尿路感染、导尿时间延长和住院时间延长等并发症的影响,并评估对改善这些患者治疗策略的潜在临床意义。

方法

在印度中部的一家三级护理医院进行了一项为期两年的观察性回顾性研究。该研究纳入了150名年龄在45至70岁之间因BPH导致LUTS的男性,参与者被平均分为两组:A组(AUR阳性)和B组(AUR阴性)。对所有患者进行了广泛的评估,包括病史、体格检查、直肠指检、超声检查以及排尿后残余(PVR)尿量评估。确定术后结果和并发症,并使用t检验进行统计分析,显著性水平为p < 0.05。

结果

研究结果表明,经历AUR的A组患者术后并发症明显高于未患AUR的B组。具体而言,A组的平均并发症发生率为60%,而B组为30%。常见并发症包括尿路感染和住院时间延长。在尿动力学参数方面,A组的最大尿流率(Qmax)显著低于B组,分别为7.5 mL/s和9.8 mL/s(p < 0.01)。A组的平均PVR尿量也明显高于B组,分别为150.4 mL和90.2 mL(p < 0.01)。这些差异突出了AUR对手术结果的影响。

结论

本研究结果突出了接受经尿道前列腺单极切除术的患者中与AUR相关的并发症风险增加。这些结果强调了谨慎选择患者和管理策略以优化结果的必要性。未来的研究应集中于扩大样本量并纳入多中心数据以提高结果的普遍性。此外,对AUR患者的长期结果和不同管理方案的有效性进行进一步研究对于改善BPH管理中的护理质量至关重要。

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