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拉美国家新冠大流行期间的自我药疗行为:一项横断面调查研究。

Self-medication Practices During the Covid-19 Pandemic in a Latin American Country: A Cross-sectional Survey Study.

机构信息

Escuela Profesional de Medicina Humana, Universidad Privada San Juan Bautista, Filial de Chincha, Ica, Perú.

Escuela Profesional de Medicina Humana, Universidad Privada San Juan Bautista, Lima, Peru.

出版信息

Inquiry. 2024 Jan-Dec;61:469580241301307. doi: 10.1177/00469580241301307.

Abstract

The COVID-19 pandemic has led many people to turn to self-medication as an accessible and convenient method of managing their health. Thus, this study sought to describe the self-medication practices (SMP) and their risk factors among the Peruvian population during the COVID-19 outbreak. A cross-sectional study was conducted from January to March, 2021, in 3 cities of Peru (Lima, Ica, and Chincha). An e-survey was distributed virtually to these populations. The association among the SMP and other variables was explored using the Chi-square test and then analyzed by the Poisson regression model (step-wise). The degree of association was represented by a prevalence ratio (PR) with its respective 95% confidence interval (95% CI). A total of 2207 participants (38.86 ± 15.1 yo) were included. 70.1% (n = 1547) were women and 70.0% (n = 1544) were from Lima. The frequency of SMP among all participants was 35.93%. In the self-medicated population, the most used drugs without a prescription were ivermectin (drops, 72.01%, n = 571), paracetamol (41.24%, n = 327), and azithromycin (25.81%, n = 284). The main factors associated with SMP were living in Chincha ( < .001; PR:1.44; 95% CI: 1.26-1.65), being divorced or widowed ( = .002; PR: 1.37; 95% CI: 1.27-1.93), being an informal employee ( < .001; PR:1.45; 95% CI: 1.23-1.71), and having symptoms of SARS-CoV-2 infection with no confirmed diagnosis ( < .001; PR: 2.17; 95% CI: 1.88-2.50). Our results showed that more than a third of all our participants self-medicated themselves. The SMP was associated mainly with residing in Chincha, not having any marital status, being informally employed, and having the presence of symptoms related to COVID-19 without diagnosis.

摘要

新型冠状病毒肺炎(COVID-19)大流行促使许多人将自我药疗作为一种易于获得和方便的健康管理方法。因此,本研究旨在描述 COVID-19 爆发期间秘鲁人群的自我药疗实践(SMP)及其危险因素。这是一项 2021 年 1 月至 3 月在秘鲁三个城市(利马、伊卡和钦查)进行的横断面研究。通过虚拟方式向这些人群分发电子调查问卷。使用卡方检验探讨 SMP 与其他变量之间的关联,然后使用泊松回归模型(逐步法)进行分析。关联程度用患病率比(PR)及其相应的 95%置信区间(95%CI)表示。共纳入 2207 名参与者(38.86±15.1 岁)。70.1%(n=1547)为女性,70.0%(n=1544)来自利马。所有参与者的 SMP 频率为 35.93%。在自我药疗人群中,未经处方使用最多的药物是伊维菌素(滴剂,72.01%,n=571)、对乙酰氨基酚(41.24%,n=327)和阿奇霉素(25.81%,n=284)。与 SMP 相关的主要因素是居住在钦查( < .001;PR:1.44;95%CI:1.26-1.65)、离婚或丧偶( = .002;PR:1.37;95%CI:1.27-1.93)、非正式雇员( < .001;PR:1.45;95%CI:1.23-1.71)以及出现 SARS-CoV-2 感染症状但未经确诊( < .001;PR:2.17;95%CI:1.88-2.50)。我们的结果表明,超过三分之一的参与者进行了自我药疗。SMP 主要与居住在钦查、没有任何婚姻状况、从事非正规职业以及出现与 COVID-19 相关但未经诊断的症状有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c89/11587187/2127322fe858/10.1177_00469580241301307-fig1.jpg

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