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[一只带来致命后果的罕见医学“变色龙”]

[A rare medical chameleon with fatal consequences].

作者信息

Wullweber Adrian, Calaminus Kristin, Beyna Torsten

机构信息

Medizinische Klinik, Evangelisches Krankenhaus Düsseldorf, Kirchfeldstraße 40, 40217, Düsseldorf, Deutschland.

出版信息

Inn Med (Heidelb). 2025 May;66(5):540-545. doi: 10.1007/s00108-024-01814-z. Epub 2024 Nov 25.

Abstract

The following case describes the relapsing and ultimately fatal outcome of DRESS (drug reaction with eosinophilia and systemic symptoms) syndrome as an often misdiagnosed drug-induced hypersensitivity reaction. The disease was complicated by progressive worsening with involvement of multiple organs and profound agranulocytosis. The main goal of this article is to raise awareness of the syndrome and its potential severity. Moreover, it outlines a number of pitfalls that may face the clinician.

摘要

以下病例描述了药物超敏反应伴嗜酸性粒细胞增多和全身症状(DRESS)综合征复发并最终导致死亡的结果,该综合征常被误诊为药物引起的超敏反应。该疾病因多器官受累和严重粒细胞缺乏而逐渐恶化。本文的主要目的是提高对该综合征及其潜在严重性的认识。此外,还概述了临床医生可能面临的一些陷阱。

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