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抗菌光动力疗法治疗糖尿病足溃疡:一项范围综述

Antimicrobial Photodynamic Therapy in the Treatment of Diabetic Foot Ulcer: A Scoping Review.

作者信息

Brandão Maria Girlane Sousa Albuquerque, Rabeh Soraia Assad Nasbine

机构信息

Department of General and Specialized Nursing, University of São Paulo, São Paulo, Brazil.

出版信息

Photobiomodul Photomed Laser Surg. 2024 Dec;42(12):725-736. doi: 10.1089/photob.2024.0013. Epub 2024 Nov 25.

DOI:10.1089/photob.2024.0013
PMID:39585755
Abstract

To map the literature about photodynamic therapy in treating diabetic foot ulcers. Diabetic foot ulcers get constantly infected, thus culminating in hospitalizations and amputations. Photodynamic therapy is an antimicrobial treatment that may assist in the healing process. A search of nine electronic information sources was made as determined by the Joanna Briggs Institute. Two independent researchers accomplished a screening of studies with the support of Rayyan. The data were analyzed through Iramutec®. The sample consisted of 27 studies. Photodynamic therapy was identified as safe and effective, with the ability to reduce pain, edema, exudate, extent of the injury region, microbial load, and the risks of infection, osteomyelitis, and amputations. The capacity of photodynamic therapy to relieve symptoms, decrease risks of complications, and accelerate the healing process highlights its potential positive impact on clinical practice.

摘要

梳理有关光动力疗法治疗糖尿病足溃疡的文献。糖尿病足溃疡常反复感染,最终导致住院治疗和截肢。光动力疗法是一种抗菌治疗方法,可能有助于伤口愈合过程。按照乔安娜·布里格斯研究所的规定,对九个电子信息源进行了检索。两名独立研究人员在Rayyan的支持下完成了对研究的筛选。通过Iramutec®对数据进行了分析。样本包括27项研究。光动力疗法被确定为安全有效,能够减轻疼痛、水肿、渗出物、损伤区域范围、微生物负荷以及感染、骨髓炎和截肢的风险。光动力疗法缓解症状、降低并发症风险和加速愈合过程的能力凸显了其对临床实践的潜在积极影响。

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Photochem Photobiol Sci. 2025 Jul;24(7):1223-1228. doi: 10.1007/s43630-025-00757-0. Epub 2025 Jul 8.