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一例罕见的左额颞部脑膜瘤创伤后硬膜下血肿及瘤内出血:采用保守方法并进行长期随访。病例说明

A rare case of posttraumatic subdural hematoma and intratumoral hemorrhage in a left frontotemporal meningioma: a conservative approach with longitudinal follow-up. Illustrative case.

作者信息

Khaleel Mansour, Sayyed Ahmad Dana, Ayyad Mohammed, Abu Al Ragheb Amer

机构信息

Department of Medicine, An-Najah National University, Nablus, State of Palestine.

Department of Medicine, Al-Quds University, Jerusalem, State of Palestine.

出版信息

J Neurosurg Case Lessons. 2024 Nov 25;8(22). doi: 10.3171/CASE24322.

Abstract

BACKGROUND

Meningiomas are common primary intracranial tumors, with associated intratumoral hemorrhage being a rare but serious complication requiring prompt diagnosis for optimal outcomes. Although spontaneous bleeding in benign meningiomas is rare, it can lead to subarachnoid hemorrhage, subdural hematoma, or intratumoral/intracerebral hemorrhage, significantly increasing morbidity and mortality. Advanced imaging and recognition of radiographic hemorrhage patterns are crucial for accurate diagnosis. Treatment is case specific, as surgical intervention is preferred for symptomatic patients, while observation might be adequate for asymptomatic cases. When surgery is not feasible, stereotactic radiotherapy or chemotherapy, which is used only as salvage therapy, is considered.

OBSERVATIONS

The authors present the case of a 78-year-old male with a history of recurrent falls. Imaging studies revealed a posttraumatic subdural hematoma and an intratumoral hemorrhage within a left frontotemporal meningioma. The patient was managed conservatively, showing significant improvement over 6 months. Notably, there was a marked reduction in both tumor size and intratumoral hemorrhage during follow-up.

LESSONS

This case highlights the importance of adopting case-specific management strategies for hemorrhagic complications associated with meningiomas. While surgery is crucial for symptomatic meningiomas, this case demonstrates that conservative methods can be effective for a subset of symptomatic patients with stable clinical conditions and manageable intracranial bleeding. https://thejns.org/doi/10.3171/CASE24322.

摘要

背景

脑膜瘤是常见的原发性颅内肿瘤,肿瘤内出血是一种罕见但严重的并发症,需要及时诊断以获得最佳治疗效果。虽然良性脑膜瘤的自发性出血很少见,但可导致蛛网膜下腔出血、硬膜下血肿或肿瘤内/脑内出血,显著增加发病率和死亡率。先进的影像学检查以及对影像学出血模式的识别对于准确诊断至关重要。治疗需根据具体情况而定,有症状的患者首选手术干预,而无症状的病例观察即可。当手术不可行时,可考虑立体定向放射治疗或仅作为挽救性治疗的化疗。

观察结果

作者报告了一例78岁男性,有反复跌倒史。影像学检查发现创伤后硬膜下血肿和左侧额颞部脑膜瘤内肿瘤内出血。该患者接受了保守治疗,6个月内有显著改善。值得注意的是,随访期间肿瘤大小和肿瘤内出血均明显减少。

经验教训

本病例强调了针对脑膜瘤相关出血性并发症采取具体病例管理策略的重要性。虽然手术对于有症状的脑膜瘤至关重要,但本病例表明,对于一部分临床状况稳定且颅内出血可控的有症状患者,保守方法可能有效。https://thejns.org/doi/10.3171/CASE24322

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5d4/11605524/1c2a8121d1af/CASE24322_figure_1.jpg

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