Schrift M J, Bandla H, Shah P, Taylor M A
J Nerv Ment Dis. 1986 Apr;174(4):203-7. doi: 10.1097/00005053-198604000-00002.
The authors studied 25 schizophrenics and 21 affectively ill, pure right-handed, male patients by using the Tactual Performance Test (TPT), a stereognosis block identification task, and an anomia task to evaluate their interhemispheric information transfer. Although both groups generally had difficulty performing the TPT, the pattern of performance deficit was not different between diagnostic groups and was not consistent with a clear-cut interhemispheric transfer problem. Schizophrenics made more naming errors and TPT preferred-hand errors than did affectively ill patients, whereas affectively ill patients were able to identify more blocks with their preferred hand than could the schizophrenics. Patient index age, illness onset age, handedness, medications received at time of testing, personal and family history of alcoholism, and family history of major mental illness did not relate to cognitive performance. It is concluded that these data are not consistent with an interhemisphere transfer deficit that is specific for schizophrenia, but they are consistent with either a nonspecific interhemisphere transfer deficit in psychoses or with a left or bilateral hemisphere impairment in schizophrenia.
作者通过使用触觉操作测验（TPT）、一种实体觉积木识别任务和一项命名障碍任务来评估25名精神分裂症患者和21名情感性精神病患者（均为单纯右利手男性患者）的半球间信息传递情况。尽管两组患者在执行TPT时总体上都有困难，但诊断组之间的表现缺陷模式并无差异，也不符合明确的半球间传递问题。精神分裂症患者比情感性精神病患者出现更多的命名错误和TPT优势手错误，而情感性精神病患者用优势手能识别的积木比精神分裂症患者更多。患者的指数年龄、发病年龄、利手、测试时所接受的药物治疗、个人和家族酗酒史以及家族重性精神病史与认知表现均无关联。结论是，这些数据与精神分裂症特有的半球间传递缺陷不一致，但与精神病中非特异性的半球间传递缺陷或精神分裂症中左侧或双侧半球损伤一致。
