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一项关于中国康复门诊患者功能障碍的性别差异的多中心研究。

A multicenter study on the sex difference of dysfunctions among rehabilitation outpatients in China.

机构信息

Department of Rehabilitation, Shenzhen Second People's Hospital, The First Affiliated Hospital, Shenzhen University School of Medicine, No. 3002, Sungang Road, Futian District, Shenzhen, 518035, Guangdong, China.

Department of Biomedical and Engineering, School of Medicine, Shenzhen University, Shenzhen, 518055, China.

出版信息

Sci Rep. 2024 Nov 25;14(1):29145. doi: 10.1038/s41598-024-80718-2.

Abstract

Dysfunction is a common clinical symptom among rehabilitation patients; however, whether there are sex differences in dysfunctions remains unclear. Therefore, this study aimed to explore this issue by examining a large sample of the population with dysfunctional problems. A multi-stage sampling scheme was used to select the rehabilitation outpatients as study participants. A total of 3415 participants from 21 medical institutions in seven cities in China were included in the final analysis. The measurement included general characteristics (age, sex, educational level, marital status, and household income) and disease-related characteristics (dysfunctions, self-care ability, vital signs, disease status, and disease course). The logistic regression was used to analyse the sex difference in dysfunctions among rehabilitation outpatients. Among 3415 rehabilitation outpatients, the mean age of participants was 45.3 years (SD:24.9), and more than half (54.0%) were male. The male patients were more likely to have cognitive impairment (OR = 1.74; 95% CI = 1.42, 2.13), speech disorders (OR = 2.00; 95% CI = 1.62, 2.48), dysphagia (OR = 1.55; 95% CI = 1.12, 2.16), and multiple dysfunctions (OR = 2.00; 95% CI = 1.57, 2.54) than female. Female patients were more likely to have motor dysfunctions (OR = 0.63; 95% CI = 0.50, 0.78). There are sex differences in dysfunctions among rehabilitation outpatients. This sex difference may provide potential clinical value for the treatment of rehabilitation patients.

摘要

功能障碍是康复患者常见的临床症状,但功能障碍是否存在性别差异尚不清楚。因此,本研究旨在通过检查大量存在功能障碍问题的人群来探讨这个问题。采用多阶段抽样方案选择康复门诊患者作为研究对象。共纳入来自中国 7 个城市 21 家医疗机构的 3415 名参与者,最终纳入 3415 名参与者进行分析。测量内容包括一般特征(年龄、性别、教育程度、婚姻状况和家庭收入)和疾病相关特征(功能障碍、自理能力、生命体征、疾病状况和病程)。采用逻辑回归分析康复门诊患者的性别与功能障碍的差异。在 3415 名康复门诊患者中,参与者的平均年龄为 45.3 岁(标准差:24.9),超过一半(54.0%)为男性。男性患者更易出现认知障碍(OR=1.74;95%CI=1.42,2.13)、言语障碍(OR=2.00;95%CI=1.62,2.48)、吞咽困难(OR=1.55;95%CI=1.12,2.16)和多种功能障碍(OR=2.00;95%CI=1.57,2.54),而女性患者更易出现运动功能障碍(OR=0.63;95%CI=0.50,0.78)。康复门诊患者的功能障碍存在性别差异。这种性别差异可能为康复患者的治疗提供潜在的临床价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4379/11589842/567285b5e9c9/41598_2024_80718_Fig1_HTML.jpg

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